GPC2 Protein (AA 24-554) (His tag)
-
- Antigène Voir toutes GPC2 Protéines
- GPC2 (Glypican 2 (GPC2))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 24-554
-
Origine
- Humain
-
Source
- HEK-293 Cells
- Purification/Conjugué
- Cette GPC2 protéine est marqué à la His tag.
- Attributs du produit
- Human Glypican 2 / GPC2 Protein, His Tag
- Pureté
- >90 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product GPC2 Protéine
-
Glypican 2 (GPC2) (AA 22-556) protein (His tag)
GPC2 Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glypican 2 (GPC2) (AA 24-554) protein (His tag)Crystallography grade GPC2 Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glypican 2 (GPC2) (AA 22-556) protein (His tag)Crystallography grade GPC2 Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Glypican 2 (GPC2) (AA 22-556) (Active) protein (His tag)GPC2 Origine: Souris Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Glypican 2 (GPC2) (AA 24-552) (Active) protein (His tag)GPC2 Origine: Macaque rhésus Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Glypican 2 (GPC2) (AA 24-553) protein (Fc Tag)GPC2 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
-
- Antigène
- GPC2 (Glypican 2 (GPC2))
- Autre désignation
- Glypican 2 (GPC2 Produits)
- Synonymes
- 2410016G05Rik Protein, glypican 2 Protein, glypican 2 (cerebroglycan) Protein, GPC2 Protein, Gpc2 Protein
- Sujet
- Glypican 2 (GPC2), also known cerebroglycan, is a glycophosphatidylinositol-linked integral membrane heparan sulfate proteoglycan found in the developing nervous system. Cerebroglycan participates in cell adhesion and is thought to regulate the growth and guidance of axons. Cerebroglycan has especially high affinity for laminin-1. GPC2 silencing inactivates Wnt/β-catenin signaling and reduces the expression of N-Myc, an oncogenic driver of neuroblastoma tumorigenesis. Immunotoxins and chimeric antigen receptor (CAR) T cells targeting GPC2 inhibit neuroblastoma growth in mouse models. A GPC3 specific antibody drug conjugate (ADC) can also inhibit neuroblastoma cell proliferation.
- Poids moléculaire
- 60.0 kDa
- NCBI Accession
- NP_689955
- Pathways
- Glycosaminoglycan Metabolic Process
-
