Complement C2 Protein (AA 21-752) (His tag)

N° du produit ABIN7013389

Détail du produit

Antigène: Complement C2

Type de proteíne: Recombinant

Attributs du protein: AA 21-752

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Complement C2 protéine est marqué à la His tag.

Attributs du produit: Human Complement Component C2 Protein, His Tag (MALS verified) (active enzyme)

Pureté: >90 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: MALS verified

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 20 mM Tris, 150 mM NaCl, pH 7.5

Stock: -20 °C

Détail du antigène

Antigène: Complement C2

Autre désignation: Complement Component C2 (Complement C2 Produits)

Synonymes: CO2 Protein, complement C2 Protein, complement component 2 (within H-2S) Protein, C2 Protein

Sujet: C2 is a major histocompatibility complex class-III protein. Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. The lectin (LP) and classical (CP) pathways are two of the three main activation cascades of the complement system. These pathways start with recognition of different pathogen- or danger-associated molecular patterns and include identical steps of proteolytic activation of complement component C4, formation of the C3 proconvertase C4b2, followed by cleavage of complement component C2 within C4b2 resulting in the C3 convertase C4b2a.

Poids moléculaire: 83.0 kDa

NCBI Accession: NP_000054