CD8 alpha Protein (AA 22-182) (His tag)
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- Antigène Voir toutes CD8 alpha (CD8A) Protéines
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 22-182
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette CD8 alpha protéine est marqué à la His tag.
- Attributs du produit
- Human CD8 alpha / CD8A Protein, His Tag
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CD8A Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
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- Antigène
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- Autre désignation
- CD8 alpha (CD8A Produits)
- Synonymes
- cd8 Protein, LOC100136450 Protein, BB154331 Protein, Ly-2 Protein, Ly-35 Protein, Ly-B Protein, Lyt-2 Protein, zgc:136643 Protein, CD8 Protein, Leu2 Protein, MAL Protein, p32 Protein, RHACD8-4 Protein, CD8a molecule Protein, uncharacterized LOC100125537 Protein, CD8 alpha Protein, CD8 antigen, alpha chain Protein, T-cell surface glycoprotein CD8 alpha chain Protein, Cd8a Protein, LOC100125537 Protein, LOC100136450 Protein, CD8A Protein, cd8a Protein, LOC100126556 Protein
- Sujet
- Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
- Poids moléculaire
- 19.5 kDa
- NCBI Accession
- NP_001759
- Pathways
- TCR Signaling
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