HHLA2 Protein (His tag)

N° du produit ABIN7121385

Détail du produit

Antigène: HHLA2 (HERV-H LTR-Associating 2 (HHLA2))

Type de proteíne: Recombinant

Origine: Cynomolgus

Source: HEK-293 Cells

Purification/Conjugué: Cette HHLA2 protéine est marqué à la His tag.

Fonction: Cynomolgus B7-H7 / HHLA2 Protein, His Tag (MALS verified)

Séquence: Ile 21 - Asn 345

Attributs du produit: Cynomolgus B7-H7, His Tag (B77-C52H3) is expressed from human 293 cells (HEK293). It contains AA Ile 21 - Asn 345 (Accession # XP_005548285.1).

Pureté: >95 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Classe de qualité: MALS verified

Information d'application

Indications d'application: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.2 kDa. The protein migrates as 60-70 kDa under reducing (R) condition due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: HHLA2 (HERV-H LTR-Associating 2 (HHLA2))

Autre désignation: B7-H7 / HHLA2 (HHLA2 Produits)

Synonymes: B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein

Sujet: Synonyms: B7-H7,HHLA2,B7 Homolog 7,
Description: B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.

Poids moléculaire: 39.2 kDa

NCBI Accession: XP_005548285