Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

C8G Protein (His tag)

C8G Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318327
  • Antigène Voir toutes C8G Protéines
    C8G (Complement Component 8, gamma Polypeptide (C8G))
    Type de proteíne
    Recombinant
    Origine
    • 3
    • 1
    • 1
    Humain
    Source
    • 4
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette C8G protéine est marqué à la His tag.
    Fonction
    Recombinant Human Complement Component C8 Gamma Chain/C8G Protein (His Tag)
    Séquence
    Gln21-Arg202
    Attributs du produit
    Recombinant Human Complement component C8 gamma chain is produced by our E.coli expression system and the target gene encoding Gln21-Arg202 is expressed with a 6His tag at the N-terminus.
    Pureté
    > 90 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product C8G Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    C8G (Complement Component 8, gamma Polypeptide (C8G))
    Autre désignation
    Complement Component C8 Gamma Chain/C8G (C8G Produits)
    Synonymes
    C8C Protein, complement C8 gamma chain Protein, complement component 8, gamma polypeptide Protein, C8G Protein, C8g Protein
    Sujet

    Background: Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.

    Synonym: Complement component C8 gamma chain,C8G

    Poids moléculaire
    22.6 kDa
    UniProt
    P07360
    Pathways
    Système du Complément
Vous êtes ici: