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GAS6 Protein (His tag)

GAS6 Origine: Humain Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
N° du produit ABIN7319834
  • Antigène Voir toutes GAS6 Protéines
    GAS6 (Growth Arrest-Specific 6 (GAS6))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 9
    • 4
    • 4
    • 1
    Humain
    Source
    • 8
    • 5
    • 2
    • 2
    • 1
    Human Cells
    Purification/Conjugué
    Cette GAS6 protéine est marqué à la His tag.
    Fonction
    Recombinant Human GAS6 (C-6His)
    Séquence
    Ala31-Ala678
    Attributs du produit
    Recombinant Human Growth Arrest-specific Protein 6 is produced by our Mammalian expression system and the target gene encoding Ala31-Ala678 is expressed with a 6His tag at the C-terminus.
    Pureté
    >95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Immobilized  Human AXL-His (Cat#C02B) at 10μg/ml (100 μl/well) can bind Human GAS6-His* (Cat#C01W).*: Biotinylated by NHS-biotin prior to testing.The ED50 of Recombinant Human GAS6-His* (Cat#C01W) is 0.04466 ug/ml.
    Top Product
    Discover our top product GAS6 Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of PBS, 10 % Glycerol, pH 7.4.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    GAS6 (Growth Arrest-Specific 6 (GAS6))
    Autre désignation
    GAS6 (GAS6 Produits)
    Synonymes
    fj34a12 Protein, zgc:63860 Protein, wu:fj34a12 Protein, MGC68463 Protein, gas6 Protein, MGC83872 Protein, GAS6 Protein, Gas-6 Protein, AXLLG Protein, AXSF Protein, growth arrest specific 6 Protein, growth arrest-specific 6 Protein, growth arrest specific 6 L homeolog Protein, growth arrest specific 6 S homeolog Protein, GAS6 Protein, gas6 Protein, gas6.L Protein, gas6.S Protein, Gas6 Protein
    Sujet

    Background: GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

    Synonym: AXLLG, AXLLGAXL stimulatory factor, AXSFAXL receptor tyrosine kinase ligand, Gas6, GAS-6, growth arrest-specific 6, growth arrest-specific protein 6

    Poids moléculaire
    72.7 kDa
    UniProt
    Q14393
    Pathways
    Signalisation RTK, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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