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HHLA2 Protein (AA 23-344) (Fc Tag)

HHLA2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7273964
  • Antigène Voir toutes HHLA2 Protéines
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 23-344
    Origine
    • 7
    • 2
    Humain
    Source
    • 7
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette HHLA2 protéine est marqué à la Fc Tag.
    Fonction
    Human B7-H7/HHLA2 Protein
    Séquence
    Ile23-Asn344
    Attributs du produit
    Recombinant Human B7-H7/HHLA2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile23-Asn344.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human CD28H, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human B7-H7, hFc Tag with the EC50 of 0.23μg/ml determined by ELISA. The affinity constant of 334 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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    Discover our top product HHLA2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Autre désignation
    B7-H7 (HHLA2 Produits)
    Synonymes
    B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein
    Sujet
    B7-H7, also known as HHLA2 (HERV-H LTR-associating 2), is a member of the B7 family of immune regulatory proteins.Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
    Poids moléculaire
    63.7 kDa. Due to glycosylation, the protein migrates to 78-100 kDa based on Tris-Bis PAGE result.
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