Folate Receptor 4 Protein (AA 20-228) (His tag)

N° du produit ABIN7274665

Détail du produit

Antigène: Folate Receptor 4 (FOLR4) (Folate Receptor 4 (Delta) (FOLR4))

Type de proteíne: Recombinant

Attributs du protein: AA 20-228

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Folate Receptor 4 protéine est marqué à la His tag.

Fonction: Human FOLR4/Juno Protein

Séquence: Gly20-Ser228

Attributs du produit: Recombinant Human FOLR4/Juno Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly20-Ser228.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Folate Receptor 4 (FOLR4) (Folate Receptor 4 (Delta) (FOLR4))

Autre désignation: FOLR4 (FOLR4 Produits)

Synonymes: 0910001L11Rik Protein, C86255 Protein, Folbp3 Protein, IZUMO1 receptor, JUNO Protein, Izumo1r Protein, IZUMO1R Protein

Sujet: Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno, formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Juno are both healthy but sterile. Here, both sperm-egg binding proteins are shown to be evolving under positive selection. Juno's presence in mammals alone, suggesting a recent mammalian-specific duplication and neofunctionalization of the ancestral folate receptor.

Poids moléculaire: 25 kDa. Due to glycosylation, the protein migrates to 30-35 kDa based on Tris-Bis PAGE result.