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GDF15 Protein (AA 197-308) (Fc Tag,Biotin)

GDF15 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7274720
  • Antigène Voir toutes GDF15 Protéines
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 197-308
    Origine
    • 14
    • 5
    • 2
    • 2
    • 1
    Cynomolgus
    Source
    • 13
    • 7
    • 3
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette GDF15 protéine est marqué à la Fc Tag,Biotin.
    Fonction
    Biotinylated Cynomolgus GDF15 Protein (Primary Amine Labeling)
    Séquence
    Ala197-Val308
    Attributs du produit
    Recombinant Biotinylated Cynomolgus GDF15 Protein (Primary Amine Labeling) is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ala197-Val308.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Cynomolgus GFRAL, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Cynomolgus GDF15, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA. See testing image for detail.
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    Discover our top product GDF15 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    Autre désignation
    GDF15 (GDF15 Produits)
    Synonymes
    GDF15 Protein, GDF-15 Protein, MIC-1 Protein, MIC1 Protein, NAG-1 Protein, PDF Protein, PLAB Protein, PTGFB Protein, SBF Protein, growth differentiation factor 15 Protein, GDF15 Protein, Gdf15 Protein
    Sujet
    Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance.
    Poids moléculaire
    37.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
    UniProt
    G7PWZ3
    Pathways
    SARS-CoV-2 Protein Interactome
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