LRRN1 Protein (AA 26-631) (His tag)

N° du produit ABIN7275196

Détail du produit

Antigène: LRRN1 (Leucine Rich Repeat Neuronal 1 (LRRN1))

Type de proteíne: Recombinant

Attributs du protein: AA 26-631

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette LRRN1 protéine est marqué à la His tag.

Fonction: Mouse LRRN1 Protein

Séquence: Ser26-Ala631

Attributs du produit: Recombinant Mouse LRRN1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser26-Ala631.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: LRRN1 (Leucine Rich Repeat Neuronal 1 (LRRN1))

Autre désignation: LRRN1 (LRRN1 Produits)

Synonymes: lrrn1 Protein, nlrr-1 Protein, nlrr-6 Protein, figler3 Protein, xnlrr-1 Protein, MGC68868 Protein, XlNLRR-6 Protein, LRRN1 Protein, FIGLER3 Protein, NLRR-1 Protein, LRCH4 Protein, 2810047E21Rik Protein, leucine rich repeat neuronal 1 L homeolog Protein, leucine rich repeat neuronal 1 Protein, leucine rich repeat neuronal 1-like L homeolog Protein, leucine rich repeat neuronal 1-like Protein, leucine rich repeat protein 1, neuronal Protein, lrrn1.L Protein, lrrn1 Protein, lrrn1-like.L Protein, lrrn1-like Protein, LRRN1 Protein, Lrrn1 Protein

Sujet: Lrrn1 is required for the formation of MHB--loss of function leads to a loss of the morphological constriction and loss of Fgf8. Cells overexpressing Lrrn1 violate the boundary and result in a loss of cell restriction between midbrain and hindbrain compartments. Lrrn1 also regulates the glycosyltransferase Lunatic Fringe, a modulator of Notch signalling, maintaining its expression in midbrain cells which is instrumental in MHB boundary formation.

Poids moléculaire: 69.28 kDa. Due to glycosylation, the protein migrates to 80-90 kDa based on Tris-Bis PAGE result.

UniProt: Q61809