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TNFRSF4 Protein (AA 20-211) (His-Avi Tag)

TNFRSF4 Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
N° du produit ABIN7275391
  • Antigène Voir toutes TNFRSF4 Protéines
    TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 20-211
    Origine
    • 28
    • 16
    • 5
    • 5
    • 3
    • 2
    • 1
    Souris
    Source
    • 36
    • 8
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette TNFRSF4 protéine est marqué à la His-Avi Tag.
    Fonction
    Mouse OX40/TNFRSF4/CD134 Protein
    Séquence
    Val20-Pro211
    Attributs du produit
    Recombinant Mouse OX40/TNFRSF4/CD134 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Val20-Pro211.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Mouse OX-40 Ligand, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Mouse OX-40, His Tag with the EC50 3.59μg/ml determined by ELISA. See testing image for detail.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
    Autre désignation
    OX40 (TNFRSF4 Produits)
    Synonymes
    TNFRSF4 Protein, ACT35 Protein, CD134 Protein, Ly-70 Protein, Ox40 Protein, TXGP1L Protein, Txgp1 Protein, OX40 Protein, TNF receptor superfamily member 4 Protein, tumor necrosis factor receptor superfamily, member 4 Protein, TNFRSF4 Protein, Tnfrsf4 Protein
    Sujet
    Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation, its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.
    Poids moléculaire
    24.2 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
    UniProt
    P47741
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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