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PLVAP Protein (AA 49-442) (His tag)

PLVAP Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
N° du produit ABIN7275502
  • Antigène Voir toutes PLVAP Protéines
    PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 49-442
    Origine
    • 5
    • 2
    • 1
    Humain
    Source
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette PLVAP protéine est marqué à la His tag.
    Fonction
    Human PLVAP Protein
    Séquence
    Tyr49-Gly442
    Attributs du produit
    Recombinant Human PLVAP Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Tyr49-Gly442.
    Pureté
    > 95 % as determined by Tris-Bis PAGE
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS, 200 mM L-arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
    Autre désignation
    PLVAP (PLVAP Produits)
    Synonymes
    MECA32 Protein, Pv1 Protein, FELS Protein, PV-1 Protein, PV1 Protein, gp68 Protein, plasmalemma vesicle associated protein Protein, Plvap Protein, PLVAP Protein
    Sujet
    Plasmalemma vesicle-associated protein (PLVAP, also called PV-1) is the only protein that forms endothelial diaphragms. PLVAP expression is very low in the normal blood-retinal barrier, however, pathological factors such as high glucose and vascular endothelial growth factor (VEGF) induce its expression, leading to the exacerbation of cellular permeability. Because the new blood vessels are fragile and leaky, PLVAP could possibly be considered a therapeutic target against retinovascular diseases.
    Poids moléculaire
    45.97 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9BX97
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