PVRIG Protein (AA 35-165) (Fc-Avi Tag,Biotin)
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- Antigène Voir toutes PVRIG Protéines
- PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 35-165
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette PVRIG protéine est marqué à la Fc-Avi Tag,Biotin.
- Fonction
- Biotinylated Mouse PVRIG Protein
- Séquence
- Ser35-Asp165
- Attributs du produit
- Recombinant Biotinylated Mouse PVRIG Protein is expressed from HEK293 with hFc tag and Avi tag at the C-Terminus.It contains Ser35-Asp165.
- Pureté
- > 95 % as determined by Tris-Bis PAGE
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 2.22 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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- Discover our top product PVRIG Protéine
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Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) protein (mFc Tag)
PVRIG Origine: Humain Hôte: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) protein (Fc Tag)PVRIG Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) protein (His tag)PVRIG Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) protein (Fc Tag)PVRIG Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 35-165) protein (Fc-Avi Tag)PVRIG Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (Active) protein (mFc Tag)PVRIG Origine: Humain Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) (Active) protein (His tag)PVRIG Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) (Active) protein (Fc Tag,AVI tag,Biotin)PVRIG Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 38-326) protein (GST tag)PVRIG Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 1-326) protein (Strep Tag)Crystallography grade PVRIG Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))
- Autre désignation
- PVRIG (PVRIG Produits)
- Synonymes
- C7orf15 Protein, PVR related immunoglobulin domain containing Protein, PVRIG Protein
- Sujet
- Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth.
- Poids moléculaire
- 42.7 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A1B0GS01
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