Osteoactivin Protein (GPNMB) (AA 23-496) (His tag)
Aperçu rapide pour Osteoactivin Protein (GPNMB) (AA 23-496) (His tag) (ABIN7491429)
Antigène
Voir toutes Osteoactivin (GPNMB) ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 23-496
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Purification/Conjugué
- Cette Osteoactivin protéine est marqué à la His tag.
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Fonction
- Recombinant Human GPNMB Protein with C-terminal 6xHis tag
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Specificité
- GPNMB (Lys23-Met496) 6xHis tag
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Attributs du produit
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Date de péremption
- 12 months
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- Osteoactivin (GPNMB)
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Autre désignation
- GPNMB
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Sujet
- The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Poids moléculaire
- predicted molecular mass of 53.9 kDa after removal of the signal peptide. The apparent molecular mass of GPNMB-His is 70-130 kDa due to glycosylation.
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UniProt
- Q14956
Antigène
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