UTP18 Protein (AA 1-556) (His tag)

N° du produit ABIN7545038

Cette protéine Recombinant UTP18 est exprimée dans HEK-293 Cells.

Aperçu rapide pour UTP18 Protein (AA 1-556) (His tag) (ABIN7545038)

Antigène: UTP18 (WD Repeat Domain 50 (UTP18))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Classe de qualité: custom-made

Détail du produit

Attributs du protein: AA 1-556

Purification/Conjugué: Cette UTP18 protéine est marqué à la His tag.

Fonction: Predefined custom protein recombinant UTP18 Protein expressed in mammalian cells.

Séquence: MPPERRRRMK LDRRTGAKPK RKPGMRPDWK AGAGPGGPPQ KPAPSSQRKP PARPSAAAAA IAVAAAEEER RLRQRNRLRL EEDKPAVERC LEELVFGDVE NDEDALLRRL RGPRVQEHED SGDSEVENEA KGNFPPQKKP VWVDEEDEDE EMVDMMNNRF RKDMMKNASE SKLSKDNLKK RLKEEFQHAM GGVPAWAETT KRKTSSDDES EEDEDDLLQR TGNFISTSTS LPRGILKMKN CQHANAERPT VARISSVQFH PGAQIVMVAG LDNAVSLFQV DGKTNPKIQS IYLERFPIFK ACFSANGEEV LATSTHSKVL YVYDMLAGKL IPVHQVRGLK EKIVRSFEVS PDGSFLLING IAGYLHLLAM KTKELIGSMK INGRVAASTF SSDSKKVYAS SGDGEVYVWD VNSRKCLNRF VDEGSLYGLS IATSRNGQYV ACGSNCGVVN IYNQDSCLQE TNPKPIKAIM NLVTGVTSLT FNPTTEILAI ASEKMKEAVR LVHLPSCTVF SNFPVIKNKN ISHVHTMDFS PRSGYFALGN EKGKALMYRL HHYSDF Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificité: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Attributs du produit: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Information d'application

Indications d'application: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -80 °C

Stockage commentaire: Store at -80°C.

Date de péremption: 12 months

Détail du antigène

Antigène: UTP18 (WD Repeat Domain 50 (UTP18))

Autre désignation: UTP18

Sujet: U3 small nucleolar RNA-associated protein 18 homolog (WD repeat-containing protein 50),FUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA. {ECO:0000269|PubMed:34516797}.

Poids moléculaire: 62.0 kDa

UniProt: Q9Y5J1

AlphaFold: Q9Y5J1