CADPS Protein (AA 1-1355) (His tag)

N° du produit ABIN7564233

Protéine Recombinant CADPS exprimée dans HEK-293 Cells.

Aperçu rapide pour CADPS Protein (AA 1-1355) (His tag) (ABIN7564233)

Antigène: CADPS (Ca++-Dependent Secretion Activator (CADPS))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Pureté: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Classe de qualité: custom-made

Détail du produit

Attributs du protein: AA 1-1355

Purification/Conjugué: Cette CADPS protéine est marqué à la His tag.

Fonction: Predefined custom protein recombinant Cadps Protein expressed in mammalian cells.

Séquence: MLDPSSSEEE SDEILEEERG KDVLGSAASG ARLSPSRTSE GSAGSAGMGG SGAGAGVGAG GGGGSGASSG GGAGGLQPSS RAGGGRPSSP SPSVVSEKEK EELERLQKEE EERKKRLQLY VFVMRCIAYP FNAKQPTDMA RRQQKISKQQ LQTVKDRFQA FLNGETQIVA DEAFMNAVQS YYEVFLKSDR VARMVQSGGC SANDSREVFK KHIEKRVRSL PEIDGLSKET VLSSWMAKFD AIYRGEEDPR KQQARMTASA ASELILSKEQ LYEMFQNILG IKKFEHQLLY NACQLDNPDE QAAQIRRELD GRLQMADQIA RERKFPKFVS KEMENMYIEE LKSSVNLLMA NLESMPVSKG GEFKLQKLKR SHNASIIDMG EESENQLSKS DVLLSFSLEV VIMEVQGLKS LAPNRIVYCT MEVEGGEKLQ TDQAEASKPT WGTQGDFSTT HALPAVKVKL FTESTGVLAL EDKELGRVIL HPTPNSPKQS EWHKMTVSKN CPDQDLKIKL AVRMDKPQNM KHSGYLWTIG KNVWKRWKKR FFVLVQVSQY TFAMCSYREK KAEPQELLQL DGYTVDYTDP QPGLEGGRAF FNAVKEGDTV IFASDDEQDR ILWVQAMYRA TGQSHKPVPP TQVQKLNAKG GNVPQLDAPI SQFSGLKDAD RAQKHGMDEF ISSNPCNFDH ASLFEMVQRL TLDHRLNDSY SCLGWFSPGQ VFVLDEYCAR NGVRGCHRHL CYLRDLLERA ENGAMIDPTL LHYSFAFCAS HVHGNRPDGI GTVTVEEKER FEEIKERLRV LLENQITHFR YCFPFGRPEG ALKATLSLLE RVLMKDIVTP VPQEEVKTVI RKCLEQAALV NYSRLSEYAK IEENQKDAEN VGRLITPAKK LEDTIRLAEL VIEVLQQNEE HHAEPHVDKG EAFAWWSDLM VEHAETFLSL FAVDMDAALE VQPPDTWDSF PLFQLLNDFL RTDYNLCNGK FHKHLQDLFA PLVVRYVDLM ESSIAQSIHR GFERESWEPV KSLTSNLPNV NLPNVNLPKV PNLPVNIPLG IPQMPTFSAP SWMAAIYDAD NGSGTSEDLF WKLDALQTFI RDLHWPEEEF GKHLEQRLKL MASDMIESCV KRTRIAFEVK LQKTSRSTDF RVPQSICTMF NVMVDAKAQS TKLCSMEMGQ EHQYHSKIDE LIEETVKEMI TLLVAKFVTI LEGVLAKLSR YDEGTLFSSF LSFTVKAASK YVDVPKPGMD VADAYVTFVR HSQDVLRDKV NEEMYIERLF DQWYNSSMNI ICTWLTDRMD LQLHIYQLKT LIRMVKKTYR DFRLQGVLDS TLNSKTYETI RNRLTVEEAT ASVSEGGGLQ GISMKDSDEE DEEDD Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.

Specificité: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Attributs du produit: Key Benefits:

• Predefined custom protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Information d'application

Indications d'application: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -80 °C

Stockage commentaire: Store at -80°C.

Date de péremption: 12 months

Détail du antigène

Antigène: CADPS (Ca++-Dependent Secretion Activator (CADPS))

Autre désignation: Cadps

Sujet: Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1),FUNCTION: Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates catecholamine loading of DCVs. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles by acting as a PtdIns(4,5)P2-binding protein that acts at prefusion step following ATP-dependent priming and participates in DCVs-membrane fusion. However, it may also participate in small clear synaptic vesicles (SVs) exocytosis and it is unclear whether its function is related to Ca(2+) triggering (By similarity). {ECO:0000250, ECO:0000269|PubMed:15820695}.

Poids moléculaire: 153.1 kDa

UniProt: Q80TJ1

AlphaFold: Q80TJ1

Pathways: Synaptic Vesicle Exocytosis