FZD8 Protein (DYKDDDDK Tag,Strep Tag)

N° du produit ABIN7596724

Cette protéine Synthetic Nanodisc FZD8 est produite dans HEK-293 Cells.

Aperçu rapide pour FZD8 Protein (DYKDDDDK Tag,Strep Tag) (ABIN7596724)

Antigène: FZD8 (Frizzled Family Receptor 8 (FZD8))

Type de proteíne: Synthetic Nanodisc

Origine: Humain

Source: HEK-293 Cells

Application: ELISA, Cryogenic electron microscopy (cryo-EM), Immunogen (Imm), Phage Display (PhD), Surface Plasmon Resonance (SPR)

Détail du produit

Purification/Conjugué: Cette FZD8 protéine est marqué à la DYKDDDDK Tag,Strep Tag.

Fonction: Human FZD8-Strep full length protein-synthetic nanodisc

Information d'application

Commentaires:

Advantages:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins
• Mammalian cell expression system ensures post- translational modifications

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: FZD8 (Frizzled Family Receptor 8 (FZD8))

Autre désignation: FZD8

Sujet: FZ-8, hFZ8
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]

Poids moléculaire: The human full length FZD8-Strep protein has a MW of 73.3 kDa

UniProt: Q9H461

Pathways: Signalisation WNT