INHBB Protein (His tag)

N° du produit ABIN809197

Détail du produit

Antigène: INHBB (Inhibin, beta B (INHBB))

Type de proteíne: Recombinant

Origine: Humain

Source: Tobacco (Nicotiana benthamiana)

Purification/Conjugué: Cette INHBB protéine est marqué à la His tag.

Application: Western Blotting (WB)

Attributs du produit: Serological Identification: The protein was electrophoresed under reducing condition on a 15 % SDS-polyacrylamide gel, transferred by electroblotting to a NC membrane and visualized by immune-detection with specific antibody Activin B.
Molecular formula: C615H910N178O177S12.
Isoelectric Point: 6,4.
Extinction coefficient: E 0.1 % (1g/L) = 1.56 (A 280 nm).
This product contains no animal-derived components or impurities. Produced by transient expression of Activin B in non-transgenic plants.

Purification: Recombinant human Activin B contains a His-tag at the N-terminal end and is purified by sequential chromatography (FPLC).

Pureté: > 97 % by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.

niveau d'endotoxine: < 0.04 EU/µg protein (LAL method)

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized protein should be reconstituted in water to a concentration of 50 ng/µL. Due to the protein nature, dimmers and multimers may be observed.

Buffer: Tris HCl 0.05 M buffer at pH 7.4

Stock: 4 °C

Détail du antigène

Antigène: INHBB (Inhibin, beta B (INHBB))

Autre désignation: INHBB (INHBB Produits)

Synonymes: actbb Protein, actbetaB Protein, inhibin Protein, inhibin, beta B Protein, inhibin beta B L homeolog Protein, inhibin beta B subunit Protein, inhibin beta B Protein, inhibin beta-B Protein, inhibin beta B chain Protein, inhbb Protein, inhbb.L Protein, INHBB Protein, Inhbb Protein, LOC100719829 Protein

Sujet: Synonyms: Activin beta-B chain, Inhibin beta B chain precursor, Inhibin, beta-2
Activins are homodimers or heterodimers of the various beta subunit isoforms, belonging to the TGF-beta family. Mature Activin B has two chains of 123 amino acids residues (betaB-betaB). Activin exhibits a wide range of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins plays a key role in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Inhibins/Activins are protein that are formed by the dimerization of two subunits, i. e. an alpha (alpha) with either beta A (betaA) - Inhibin A or beta B (betaB) - Inhibin B. The subunits betaA and betaB can also form homodimers or heterodimers called Activin: Activin A (betaA -betaA), Activin B (betaB -betaB) and Activin AB (betaA -betaB). The Activin gene family comprises the additional, but poorly characterized members’ Activin betaC (betaC), beta D (betaD) and beta E (betaE). As with other members of the super-family, Activins interact with two types of cell surface trans-membrane receptors (Types I and II) which have intrinsic serine/threonine kinase activities in their cytoplasmic domains, Activin type 1 receptors, ACVR1, ACVR1B, ACVR1C and Activin type 2 receptors, ACVR2A, ACVR2B.

Poids moléculaire: 14 kDa

ID gène: 3625, 147390

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion