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IL1R1 Protéine

IL1R1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 98 % pure Active
N° du produit ABIN935559
  • Antigène Voir toutes IL1R1 Protéines
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 18
    • 10
    • 9
    Humain
    Source
    • 14
    • 10
    • 4
    • 4
    • 3
    • 2
    Escherichia coli (E. coli)
    Séquence
    MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
    Attributs du produit
    Purified recombinant Human IL1 R alpha protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to inhibit the IL-1alpha stimulation of Mouse D10S cell. The expected ED50 is 20-40 ng/mL in the presence of 50 pg/mL of IL-1alpha.
    Pureté
    > 98 % pure
    niveau d'endotoxine
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IL1R1 Protéine
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in water to a concentration of 0.1 to 1.5 g/mL. Do not vortex.
    Buffer
    Lyophilized from 5 mM Tris, pH 8.0, with 25 mM NaCl.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    RT/-20 °C
  • Antigène
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    Autre désignation
    IL1R alpha (IL1R1 Produits)
    Synonymes
    CD121A Protein, D2S1473 Protein, IL-1R-alpha Protein, IL1R Protein, IL1RA Protein, P80 Protein, CD121a Protein, CD121b Protein, IL-iR Protein, Il1r-1 Protein, DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, interleukin 1 receptor type 1 Protein, interleukin 1 receptor, type I Protein, interleukin 1 receptor-like 1 Protein, IL1R1 Protein, Il1r1 Protein, Il1rl1 Protein
    Sujet
    Interleukin-1 receptor antagonist (IL1RA) is a naturally occurring inflammatory inhibitor protein. It inhibits the activity of IL1a and IL1beta by competitively blocking binding to their type I and type II receptors. IL1Ra is produced by corneal epithelial cells, monocytes, neutrophils, macrophages, and fibroblasts. Therapeutically, IL1Ra may help in the treatment of sepsis, cachexia, rheumatoid arthritis, chronic myelogenous leukemia, asthma, psoriasis, and inflammatory bowel disease.
    Alternative Names: IL 1 protein, IL 1, ICIL-1RA protein, Interleukin 1R alpha protein, IL-1R alpha protein, IL1, IL-1RN protein, IRAP protein, IL-1, IL-1 protein, IL-1Ra protein
    Poids moléculaire
    17.2 kDa
    Pathways
    Signalisation NF-kappaB, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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