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CCL15 Protéine

CCL15 Origine: Humain Hôte: Escherichia coli (E. coli) > 97 % by SDS-PAGE and HPLC analyses. Active
N° du produit ABIN988168
  • Antigène Voir toutes CCL15 Protéines
    CCL15 (Chemokine (C-C Motif) Ligand 15 (CCL15))
    Activité biologique
    Active
    Origine
    Humain
    Source
    • 7
    • 4
    • 2
    • 2
    Escherichia coli (E. coli)
    Séquence
    QFTNDAETEL MMSKLPLENP VVLNSFHFAA DCCTSYISQS IPCSLMKSYF ETSSECSKPG VIFLTKKGRQ VCAKPSGPGV QDCMKKLKPY S
    Attributs du produit
    Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human T-lymphocytes is less than 10 ng/ml, corresponding to a specific activity of >, 1.0 × 105 IU/mg.
    Pureté
    > 97 % by SDS-PAGE and HPLC analyses.
    niveau d'endotoxine
    Level Less than 1EU/µg of rHuMIP-5/CCL15 as determined by LAL method
    Top Product
    Discover our top product CCL15 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
    Stock
    4 °C
  • Antigène
    CCL15 (Chemokine (C-C Motif) Ligand 15 (CCL15))
    Autre désignation
    MIP-5/CCL15 (CCL15 Produits)
    Synonymes
    HCC-2 Protein, HMRP-2B Protein, LKN-1 Protein, LKN1 Protein, MIP-1 delta Protein, MIP-1D Protein, MIP-5 Protein, MRP-2B Protein, NCC-3 Protein, NCC3 Protein, SCYA15 Protein, SCYL3 Protein, SY15 Protein, C-C motif chemokine ligand 15 Protein, CCL15 Protein
    Sujet
    CCL15, a new human CC chemokine, was isolated from a human fetal spleen cDNA library. CCL15 cDNA encodes a predicted 113 amino acid (aa) protein containing a putative signal peptide of 21 amino acids that is cleaved to generate a 92 aa residue mature protein. Within the CC family members, human CCL15 shares 45%, 44%, 35%, and 30% aa homology with mouse C10, human MPIF-1, human HCC-1, and mouse MIP-1γ, respectively. The gene for MIP-5 is found on chromosome 17 where the genes for most of the human CC chemokines are located. Human CCL15 is expressed in T and B lymphocytes, NK cells, monocytes and monocyte-derived dendritic cells. Human MIP-5 is chemotactic for T cells and monocytes and has been shown to induce calcium flux in human CCR-1-transfected cells. Synonym: MIP-5/CCL15, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 100mM NaCl.
    Poids moléculaire
    10.1 kDa, a single non-glycosylated polypeptide chain containing 92 amino acids.
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