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An analysis of eight structures of mitochondrial bc(1) with bound quinol oxidation (Q(o)) site inhibitors revealed that the presence of inhibitors causes a bidirectional repositioning of the cd1 helix in the cytochrome b subunit.
mt-Cytb mutations were studied in a mouse cultured cell model. Complex III assembly was impeded and caused a severe reduction in the amount of Complex I.
The effects of mutation in mitochondrially encoded cytochrome b are reviewed.
Mitochondrial mutation m.15804T>C in the mtCYB gene in a family with fibromyalgia is associated with NLRP3 (Montrer NLRP3 Anticorps)-inflammasome activation.
These results indicate that miR (Montrer MLXIP Anticorps)-151a-5p may participate in the regulation of cellular respiration and ATP production through targeting Cytb.
This study suggests that, in part, polymorphisms in the MT-ATP6 (Montrer MT-ATP6 Anticorps) and MT-CYB genes may contribute to the unexpected fertilization failure.
The polymorphisms of CYTB as a very useful DNA marker were significantly different between different geographical Uyghur
Significant elevation of ERalpha (Montrer ESR1 Anticorps) and MTCYB transcript levels in premenopausal leiomyomas and its association with ERalpha (Montrer ESR1 Anticorps), -397 CC genotype suggests the mitochondrial-mediated role of estrogen as the promoter of leiomyoma tumorigenesis.
Data show that homoplasmic G6709A (MT-CO1) and G14804A (MT-CYB) alterations cause amino acid changes in the highly conserved residues.
mitocryptide-2 (MCT-2 (Montrer SLC16A7 Anticorps)) and its human homolog hMCT-2 are cryptides that activate neutrophils
The other proband had a non-synonymous G15221A mutation in the cytochrome b gene.
In a mitochondrial myopathy patient, a novel stop-codon mutation (G15761A) was found in the mitochondrial DNA (mtDNA)-encoded cytochrome b gene, resulting in loss of the last 41 amino acids of the protein and complex III deficiency
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity).