Profil protéine

This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.

Alternative names and synonyms associated with ANGPTL4

• angiopoietin like 4 (ANGPTL4) anticorps
• angiopoietin-like 4 (Angptl4) anticorps
• angiopoietin-like 4 (angptl4) anticorps

• ANGPTL2 anticorps
• ANGPTL4 anticorps
• Arp4 anticorps
• Bk89 anticorps
• fiaf anticorps
• Afficher tous les alias de synonymes
• Hfarp anticorps
• im:7144703 anticorps
• Ng27 anticorps
• NL2 anticorps
• Pgar anticorps
• Pgarg anticorps
• Pp1158 anticorps
• si:rp71-39b20.7 anticorps

Protein level used designations for ANGPTL4

PPARG angiopoietin related protein , angiopoietin-like protein 4 , angiopoietin-related protein 4 , fasting-induced adipose factor , hepatic angiopoietin-related protein , hepatic fibrinogen/angiopoietin-related protein , peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein , 425O18-1 , fibrinogen/angiopoietin-related protein , major histocompatibility complex region NG27 , secreted protein Bk89 , HFARP , PPARG angiopoietin-related protein , angiopoietin-like 4 , angiopoietin-like secreted glycoprotein 4 , angiopoietin-related protein 4-like , angiopoietin-like 4 protein