anti-Souris FDFT1 anticorps pour Enzyme Immunoassay

Recommended FDFT1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) Anticorps
  • FDFT1
  • DKFZp459C1712
  • SQS
  • SS
  • DGPT
  • ERG9
  • fdft1
  • farnesyl-diphosphate farnesyltransferase 1
  • squalene synthase
  • farnesyl diphosphate farnesyl transferase 1
  • FDFT1
  • fdft1
  • LOC100560926
  • Fdft1
Épitope
N-Term
12
10
10
10
10
9
7
7
7
5
5
5
4
4
2
1
1
Reactivité
Humain, Souris
102
31
15
4
3
2
2
2
2
1
1
1
Hôte
Lapin
99
15
Clonalité
Polyclonal
Conjugué
Cet anticorp FDFT1 est non-conjugé
11
11
7
6
6
6
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
110
61
59
14
12
9
6
5
3
2
1
Fournisseur
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N° du produit ABIN357711
$ 390.50
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General

Antigène Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) Anticorps
Épitope N-Term
(12), (10), (10), (10), (10), (9), (7), (7), (7), (5), (5), (5), (4), (4), (2), (1), (1)
Reactivité Humain, Souris
(102), (31), (15), (4), (3), (2), (2), (2), (2), (1), (1), (1)
Hôte Lapin
(99), (15)
Clonalité
Polyclonal
Conjugué Cet anticorp FDFT1 est non-conjugé
(11), (11), (7), (6), (6), (6)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(110), (61), (59), (14), (12), (9), (6), (5), (3), (2), (1)
Pubmed 6 références disponible
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Détail du produit anti-FDFT1 anticorps

Détail du antigène FDFT1 Information d'application Stockage References for anti-FDFT1 antibody (ABIN357711) Images
Specificité This antibody detects FDFT1 (N-term).
Purification Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogène This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human FDFT1.
Isotype Ig Fraction

Détail du antigène FDFT1

Détail du produit anti-FDFT1 anticorps Information d'application Stockage References for anti-FDFT1 antibody (ABIN357711) Images Haut de la page
Antigène
Autre désignation Squalene Synthetase (FDFT1 Antibody Extrait)
Sujet FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.Synonyms: FDFT1, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, SQS, SS
Poids moléculaire 48115 Da
ID gène 2222, 5874
UniProt P37268
Pathways Regulation of Lipid Metabolism by PPARalpha

Information d'application

Détail du produit anti-FDFT1 anticorps Détail du antigène FDFT1 Stockage References for anti-FDFT1 antibody (ABIN357711) Images Haut de la page
Indications d'application ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-FDFT1 anticorps Détail du antigène FDFT1 Information d'application References for anti-FDFT1 antibody (ABIN357711) Images Haut de la page
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-FDFT1 antibody (ABIN357711)

Détail du produit anti-FDFT1 anticorps Détail du antigène FDFT1 Information d'application Stockage Images Haut de la page
Background publications

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002

Soltis, McMahon, Caplan, Dudas, Chamberlin, Vattay, Dottavio, Rucker, Engstrom, Cornell-Kennon: "Expression, purification, and characterization of the human squalene synthase: use of yeast and baculoviral systems." dans: Archives of biochemistry and biophysics, Vol. 316, Issue 2, pp. 713-23, 1995

Summers, Karst, Charles: "Cloning, expression and characterisation of the cDNA encoding human hepatic squalene synthase, and its relationship to phytoene synthase." dans: Gene, Vol. 136, Issue 1-2Che, pp. 185-92, 1994

Jiang, McKenzie, Conrad, Shechter: "Transcriptional regulation by lovastatin and 25-hydroxycholesterol in HepG2 cells and molecular cloning and expression of the cDNA for the human hepatic squalene synthase." dans: The Journal of biological chemistry, Vol. 268, Issue 17, pp. 12818-24, 1993

Robinson, Tsay, Kienzle, Smith-Monroy, Bishop: "Conservation between human and fungal squalene synthetases: similarities in structure, function, and regulation." dans: Molecular and cellular biology, Vol. 13, Issue 5, pp. 2706-17, 1993

Zinkl, Roberts, Shea, Lasmanis: "Toxicity of acephate and methamidophos to dark-eyed juncos." dans: Archives of environmental contamination and toxicology, Vol. 10, Issue 2, pp. 185-92, 1981

Images

Détail du produit anti-FDFT1 anticorps Détail du antigène FDFT1 Information d'application Stockage References for anti-FDFT1 antibody (ABIN357711) Haut de la page
Images (Fournisseur)
 image for anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (N-Term) antibody (ABIN357711) anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (N-Term) antibody
 image for anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (N-Term) antibody (ABIN357711) anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (N-Term) antibody (Image 2)