Aperçu des produits pour MED26 Protéines (MED26)

Full name:: Mediator Complex Subunit 26 Protéines (MED26)

Chez www.anticorps-enligne.fr sont 4 Mediator Complex Subunit 26 (MED26) Protéines de 2 de différents fournisseurs disponibles. De plus, nous expédions MED26 Anticorps (64) et MED26 Kits (13) et beaucoup plus de produits pour cette protéine. Un total de 88 MED26 produits sont actuellement listés.

Synonymes:: 5730493L18Rik, AI414941, AW495270, crsp7, CRSP70, med26, Slc35e1, wu:fe06c07, wu:fi75a09, zgc:55993

afficher tous les protéines	Gène	GeneID	UniProt
	MED26	9441	O95402
	MED26	70625	Q7TN02
Rat MED26	MED26	306328
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MED26 Protéines (MED26) par origine

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Pathways pertinentes pour MED26 Protéines

Regulation of Lipid Metabolism by PPARalpha

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Plus protéines pour MED26 partenaires d'interaction

Human Mediator Complex Subunit 26 (MED26) interaction partners

EAF1 (239-268) and TAF7 (Montrer TAF7 Protéines) (205-235) peptide interactions were both mapped to the same groove formed by H3 and H4 helices of MED26 N-terminal domain.
the MED26-NTD functions as a molecular switch in the exchange of TBP-associated factor 7 (TAF7 (Montrer TAF7 Protéines)) for LEC to facilitate the transition from initiation to elongation during transcription of a subset of snRNA genes
MED26 can function as a molecular switch that interacts first with TFIID in the Pol II initiation complex and then exchanges TFIID for complexes containing ELL/EAF and P-TEFb to facilitate transition of Pol II into the elongation stage of transcription.
Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation
findings identify MED19 (Montrer MED19 Protéines)/MED26 as a probable composite REST interface in Mediator and further clarify the mechanistic basis by which Mediator facilitates REST-imposed epigenetic restrictions on neuronal gene expression

Profil protéine MED26

Profil protéine

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

Alternative names and synonyms associated with MED26

mediator of RNA polymerase II transcription subunit 26 (LOC725023)
cofactor required for Sp1 transcriptional activation, subunit 7 (crsp7)
mediator complex subunit 26 (MED26)
mediator complex subunit 26 (Med26)
mediator complex subunit 26 L homeolog (med26.L)

5730493L18Rik Protéine
AI414941 Protéine
AW495270 Protéine
crsp7 Protéine
CRSP70 Protéine
med26 Protéine
Slc35e1 Protéine
wu:fe06c07 Protéine
wu:fi75a09 Protéine
zgc:55993 Protéine

Protein level used designations for MED26

mediator of RNA polymerase II transcription subunit 26 , CRSP complex subunit 7 , CRSP70 , mediator complex subunit 26 , ARC70 , activator-recruited cofactor 70 kDa component , cofactor required for Sp1 transcriptional activation subunit 7 , cofactor required for Sp1 transcriptional activation, subunit 7 (70kD) , cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa , transcriptional coactivator CRSP70 , solute carrier family 35, member E1 , CRSP70-like protein

GENE ID	SPECIES
725023	Apis mellifera
406332	Danio rerio
9441	Homo sapiens
70625	Mus musculus
306328	Rattus norvegicus
399180	Xenopus laevis
506331	Bos taurus

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