Aperçu des produits pour anti-HEY2 (HEY2) Anticorps

Full name:: anti-Hairy/enhancer-of-Split Related with YRPW Motif 2 Anticorps (HEY2)

Chez www.anticorps-enligne.fr sont 80 Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) Anticorps de 18 de différents fournisseurs disponibles. De plus, nous expédions HEY2 Protéines (6) et beaucoup plus de produits pour cette protéine. Un total de 93 HEY2 produits sont actuellement listés.

Synonymes:: bHLHb32, CHF1, GRIDLOCK, grl, Herp1, hesr2, Hrt2, zgc:136746

afficher tous les anticorps	Gène	GeneID	UniProt
	HEY2	23493	Q9UBP5
	HEY2	15214	Q9QUS4
	HEY2	155430
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Pathways pertinentes pour anti-HEY2 Anticorps

Regulation of Muscle Cell Differentiation

Plus produit pour HEY2 Anticorps

anti-HEY2 Anticorps mieux référencés

Zebrafish (Danio rerio) Polyclonal HEY2 Primary Antibody pour WB - ABIN1881411 : Winkler, Elmasri, Klamt, Volff, Gessler: Characterization of hey bHLH genes in teleost fish. dans Development genes and evolution 2003 (PubMed)
Show all 3 Pubmed References
Cow (Bovine) Polyclonal HEY2 Primary Antibody pour ELISA - ABIN4317227 : Tang, Urs, Liaw: Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site. dans Circulation research 2008 (PubMed)

Plus d’anticorps contre HEY2 partenaires d’interaction

Human Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) interaction partners

The findings identify HEY2 as a novel component of the NKX2-5 (Montrer NKX2-5 Anticorps) cardiac transcriptional network.
HEY2 as a promising biomarker for unfavorable outcomes and a novel therapeutic target for the clinical management of HCC (Montrer FAM126A Anticorps)
Genetic variation of HEY2 is associated with Brugada syndrome through alteration of ion channel expression in the cardiac ventricular wall.
Individuals with HEY2 duplications should be screened for congenital heart defects.
HEY2 CC genotype may be a favorable prognostic marker for BrS, protectively acting to prevent ventricular fibrillation presumably by regulating the repolarization current.
Overexpression of HEY1 (Montrer HEY1 Anticorps) and HEY2 in esophageal squamous cell carcinoma (ESCC) is correlated to different indices of poor prognosis, and it is extrapolated that such overexpression is important in progression and development of ESCC tumorigenesis.
bone morphogenic proteins within the serum of cell culture medium are potent inducers of endothelial Hey1 (Montrer HEY1 Anticorps) and Hey2 gene expression within the first few hours after medium change
a new HRD1 (Montrer SYVN1 Anticorps)-associated membrane protein named HERP2 (Montrer HEY1 Anticorps), which is homologous to the previously identified HRD1 (Montrer SYVN1 Anticorps) partner HERP1. Despite sequence homology, HERP2 (Montrer HEY1 Anticorps) is constitutively expressed in cells, whereas HERP1 is highly induced by ER stress.
Data indicate that culture abrogated differential gene expression in part due to gradual loss of canonical Notch (Montrer NOTCH1 Anticorps) activity and HEY2 expression.
Common variants at SCN5A (Montrer SCN5A Anticorps)-SCN10A (Montrer SCN10A Anticorps) and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

Mouse (Murine) Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) interaction partners

Data implied that Hey2 function is restricted to transient amplifying cells of the ameloblast cell lineage and that Hey1 (Montrer HEY1 Anticorps) plays a role in the composition of the subodontoblastic layer, in addition to ameloblast differentiation.
Hey proteins mechanistically repress target genes via histone deacetylase (Montrer HDAC1 Anticorps) recruitment and histone deacetylation.
Results suggest that bone morphogenetic protein signaling plays pivotal roles in retinal progenitor cell differentiation into late differentiating retinal cell types and in Muller glia maturation; these effects were mediated, at least in part, by Hey2
Hey1 (Montrer HEY1 Anticorps) and Hey2 in endothelial cells play important roles in vascular development.
findings indicate that Hey1 (Montrer HEY1 Anticorps) and Hey2 control the spatial and temporal pattern of auditory HC differentiation.
CHF1/Hey2 may contribute to Brugada syndrome.
Common variants at SCN5A (Montrer SCN5A Anticorps)-SCN10A (Montrer SCN10A Anticorps) and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.
Data indicate that Hairy and Enhancer of Split-related with YRPW motif (HEY)2 decreases skeletal mass and regulates bone remodeling in male mice.
Data indicate that Notch1 (Montrer NOTCH1 Anticorps) and Notch2 (Montrer NOTCH2 Anticorps) are expressed and localized in the nuclei of the label-retaining cells (LRCs), and the expression of Notch (Montrer NOTCH1 Anticorps)-inducible genes, Hes1 (Montrer HES1 Anticorps) and Hey2, was elevated in LRCs.
Survivor mice lacking the Hesr2 gene exhibit fibrosis in the aortic valve and ventricle in adulthood, thus suggesting that Hesr2 plays an important role in maintaining the homeostasis of the aortic valve and ventricle.

Zebrafish Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) interaction partners

essential role for Hey2 upstream of Notch in hematopoietic stem cell formation
Forms a complex with Gata5 through the carboxyl region and can repress Gata5-mediated transcription.
The snrk (Montrer SNRK Anticorps)-1 gene acts downstream or parallel to notch (Montrer NOTCH1 Anticorps) and upstream of gridlock during artery-vein specification

HEY2 profil antigène

Antigen Summary

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

Alternative names and synonyms associated with HEY2

hes related family bHLH transcription factor with YRPW motif 2 (HEY2) anticorps
hairy/enhancer-of-split related with YRPW motif 2 (Hey2) anticorps
hes-related family bHLH transcription factor with YRPW motif 2 (hey2) anticorps
hes-related family bHLH transcription factor with YRPW motif 2 (Hey2) anticorps

bHLHb32 anticorps
CHF1 anticorps
GRIDLOCK anticorps
grl anticorps
Herp1 anticorps
hesr2 anticorps
Hrt2 anticorps
zgc:136746 anticorps

Protein level used designations for HEY2

, , , , , , , , , , , , , , , , , , hairy/enhancer-of-split related with YRPW motif protein 2 HES-related repressor protein 1 HES-related repressor protein 2 HESR-2 HRT-2 cardiovascular basic helix-loop-helix factor 1 cardiovascular helix-loop-helix factor 1 class B basic helix-loop-helix protein 32 hCHF1 hHRT2 hairy and enhancer of split-related protein 2 hairy-related transcription factor 2 protein gridlock homolog Hairy-E(spl)-related with YRPW motif 2 hairy and enhancer of split related 2 mHRT2 Herp2 gridlock protein gridlock

GENE ID	SPECIES
100152404	Sus scrofa
23493	Homo sapiens
15214	Mus musculus
58146	Danio rerio
484115	Canis lupus familiaris
538619	Bos taurus
155430	Rattus norvegicus
421718	Gallus gallus

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Show all anti-Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2) Anticorps with Pubmed References