Profil protéine

This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with ZFHX3

• zinc finger homeobox 3 (zfhx3) anticorps
• zinc finger homeobox 3 (ZFHX3) anticorps
• AT-binding transcription factor1 (ATBF1/ZFHX4b) anticorps
• zinc finger homeobox 3 (Zfhx3) anticorps

• A230102L03Rik anticorps
• Atbf1 anticorps
• ATBT anticorps
• mKIAA4228 anticorps
• RGD1560268 anticorps
• Afficher tous les alias de synonymes
• WBP9 anticorps
• zax-2 anticorps
• ZFHX3 anticorps
• ZNF927 anticorps

Protein level used designations for ZFHX3

zinc finger homeobox 3 , zinc finger homeobox protein 3-like , AT-binding transcription factor 1 , AT-binding transcription factor1 , AT motif-binding factor 1 , ZFH-3 , alpha-fetoprotein enhancer binding protein , alpha-fetoprotein enhancer-binding protein , zinc finger homeobox protein 3 , zinc finger homeodomain protein 3 , AT motif binding factor 1 , AT motif-binding factor