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Human Polyclonal SPR Primary Antibody pour WB - ABIN520456
Lange, Geerts, Feith, Mocz, Koster, Bachmann: Novel interaction of ornithine decarboxylase with sepiapterin reductase regulates neuroblastoma cell proliferation. dans Journal of molecular biology 2014
Human Polyclonal SPR Primary Antibody pour ELISA, WB - ABIN562987
Balasubramanian, Deng, Doudney, Hampton, Kennedy: Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line. dans Neuropharmacology 2015
Human Polyclonal SPR Primary Antibody pour WB - ABIN653908
Maddens, Ghesquière, Vanholder, Demon, Vanmassenhove, Gevaert, Meyer: Chitinase-like proteins are candidate biomarkers for sepsis-induced acute kidney injury. dans Molecular & cellular proteomics : MCP 2012
These results reveal a critical role for endosomal signaling of the NK1R (Montrer TACR1 Anticorps) in the complex pathophysiology of pain.
The percentages of SP+ and NK1R (Montrer TACR1 Anticorps)+ expression populations of monocytes, helper T cells, natural killer T cells and basophils in peripheral blood of eczema patients were markedly elevated.
elevated plasma SP level, up-regulated expression of SP and NK1R (Montrer TACR1 Anticorps) indicate that the SP/NK1R (Montrer TACR1 Anticorps) complex is important in the development of Atopic dermatitis.
Expression of NK1R (Montrer TACR1 Anticorps) increases in the eosinophils of chronic spontaneous urticaria (CSU) patients. Blockers of NK1R (Montrer TACR1 Anticorps) might be used for CSU treatment.
NK-1R (Montrer TACR1 Anticorps) may positively regulate melanogenesis through Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) signaling pathway.
This study revealed for the first time an increase of Mast Cells -nerve association and NK1R (Montrer TACR1 Anticorps) expression on Mast Cells during Allergic Rhinitis as well as nerve fibres containing receptors for mass cells.
Kinase activation led to increased MMP-2 (Montrer MMP2 Anticorps) and MT1-MMP (Montrer MMP14 Anticorps) expression and melanoma cell migration induced by hHK-1 (Montrer HOOK1 Anticorps). Thus, hHK-1 (Montrer HOOK1 Anticorps) and the NK1 receptor (Montrer TACR1 Anticorps) are critical to melanoma cell migration and each may be a promising chemotherapeutic target
Within a small cohort of patients who presented for treatment,a novel gene was identified that appears to contribute to anorexia nervosa pathophysiology, TACR1 (Montrer TACR1 Anticorps).
NK1 receptor (Montrer TACR1 Anticorps) expression is increased in colonic tissues from experimental colitis models and in the colon of Irritable Bowel Disease patients.
High Truncated Neurokinin-1 Receptor expression is associated with Neuroblastoma (Montrer ARHGEF16 Anticorps).
Our results suggest that the hypertension with fluctuation and bradycardia of Spr(-/-) mice would be caused by an imbalance of sympathetic and parasympathetic input and impaired nitric oxide production in endothelial cells.
SPR-mediated reduction of sepiapterin and redox cycling occur by distinct mechanisms
biopterin contents in the brains of these knock-out mice were moderately decreased from postnatal day 0 (P0) and remained constant up to P21 (Montrer D4S234E Anticorps)
These data suggest an essential role of SPR in the biosynthesis of BH4, and that the SPR gene could be a candidate gene for PARK3.
this study demonstrates an important role of endothelial SPR in modulating tetrahydrobiopterin and nitric oxide bioavailability
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
, substance-P receptor
, tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
, sepiapterin reductase
, short chain dehydrogenase/reductase family 38C, member 1
, 7,8-dihydrobiopterin:NADP+ oxidoreductase
, Sepiapterin reductase
, sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)