Aperçu des produits pour anti-Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2) Anticorps

Human Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2) interaction partners

1. The authors findings indicate that the SNP rs4238326 in ALDH1A2 gene may potentially modify individual susceptibility to knee OA in the Chinese population.

2. high transcription activities of ALDH1A2, ALDH1A3 (Montrer ALDH1A3 Anticorps) and ALDH1L1 (Montrer ALDH1L1 Anticorps) predicted worsen overall survival in gastric cancer patients

3. Data show that hRALDH2 is not inhibited by its oxidation product, all-trans-RA, suggesting the absence of a negative feedback regulatory loop. Expression of the Raldh2 gene is known to be regulated by RA itself, suggesting that the main regulation of the hRALDH2 activity level is transcriptional.

4. Study shows no evidence that genetic variants alter prostate cancer incidence, but show that SNPs in the ALDH1A2 gene affect prostate cancer mortality.

5. a critical role of ALDH1A2-RAR (Montrer RARA Anticorps) signaling in the pathogenesis of head and neck cancer.

6. High expression of ALDH1A2 and ALDH1B1 (Montrer ALDH1B1 Anticorps) mRNA was found to be significantly correlated to worser survival in all NSCLC patients.

7. the distribution of RALDH1 (Montrer ALDH1A1 Anticorps), RALDH2, and RALDH3 (Montrer ALDH1A3 Anticorps) in the postnatal eye was determined.

8. ALDH1A2 is involved in the regulation of cancer stem cell properties in neuroblastoma (Montrer ARHGEF16 Anticorps).

9. Genetic association replicative and exploratory studies identify SNPs in ADA (Montrer ADA Anticorps) and MTR (Montrer MTR Anticorps) highly associated with isolated Neural tube defects (NTD)and SNP in ARID1A (Montrer ARID1A Anticorps) and ALDH1A2 associated with NTDs in whites and African Americans respectively.

10. At the transcript level, the cisplatin + DEAB-resistant cells showed upregulated mRNA expression levels for ALDH1A2, ALDH1A3 (Montrer ALDH1A3 Anticorps) isozymes and CD44 (Montrer CD44 Anticorps) indicating the involvement of these markers in conferring chemoresistance

Zebrafish Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2) interaction partners

1. Zebrafish foxc1a plays a crucial role in early somitogenesis by restricting the expression of Raldh2 directly.

2. The novel aldh1a2 reporter line is driven by the complete set of regulatory sequences required for zebrafish development, reports novel sources of RA synthesis, and identifies the source of RA that promotes vertebral ossification.

3. aldh1a2 participate to a positive loop required for branchial arches development in zebrafish

4. Aldh1a2 is the primary aldehyde dehydrogenase acting during pancreas development and maternal Aldh1a2 activity persists in aldh1a2(um22) and aldh1a2(i26) mutant embryos.

5. Studies indicate that raldh2 expression is critical for the formation of wound epithelium and blastema.

Mouse (Murine) Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2) interaction partners

1. data do not support the hypothesis that retinal itself represses weight gain and adipogenesis independently of RA. Instead, the data indicate that Raldh1 (Montrer ALDH1A1 Anticorps) functions as a retinal and atRA-independent promoter of adiposity during adolescence, and enhances adiposity through pre-adipocyte cell autonomous actions

2. these studies identify Notch (Montrer NOTCH1 Anticorps) signaling in dendritic cells as a crucial balancer of Th17/iTreg, which depends on the direct regulation of Aldh1a2 (Montrer ALDH1A1 Anticorps) transcription in dendritic cells

3. ALDH2 (Montrer ALDH2 Anticorps) mutation displays an inverse correlation of coronary collateral vessel formation in patients.

4. Data suggest that retinoic acid and GM-CSF (Montrer CSF2 Anticorps)-induced retinal dehydrogenase 2 (RALDH2) expression in dendritic cells requires cooperative binding of transcription factor Sp1 (Montrer SP1 Anticorps) via the RA receptor/retinoid X receptor (Montrer RXRB Anticorps) complex to the Aldh1a2 (Montrer ALDH1A1 Anticorps) promoter.

5. all three proteins (RDH10 (Montrer RDH10 Anticorps), RALDH2, and CRABP2 (Montrer CRABP2 Anticorps)) appeared to be required for ATRA production induced by activation of PPARgamma (Montrer PPARG Anticorps)

6. Defects in interdigital programmed cell death and digit separation in Hoxa13 (Montrer HOXA13 Anticorps) mutant mice may be caused in part by reduced levels of RA signaling stemming from a loss in the direct regulation of Aldh1a2 (Montrer ALDH1A1 Anticorps)

7. Raldh1 (Montrer ALDH1A1 Anticorps) and Raldh3 (Montrer ALDH1A3 Anticorps) influence enteric nervous system structure and function and heterozygosity for Raldh2 causes ENS defects

8. ALDH1A2 expression was highest in ALDH(very-br) cells, intermediate in ALDH(dim) cells, and lowest in ALDH(br) cells.

9. Upregulation of retinal dehydrogenase 2 in alternatively activated macrophages during retinoid-dependent type-2 immunity to helminth infection in mice.

10. rendered Fgfr2IIIb (Montrer FGFR2 Anticorps)(-/-) embryos haploinsufficient for the Raldh2 and examined these embryos for the incidence and severity of duodenal atresia