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Aperçu des produits pour anti-DDX3X (DDX3X) Anticorps

Full name:: anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked Anticorps (DDX3X)

Chez www.anticorps-enligne.fr sont 179 DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) Anticorps de 31 de différents fournisseurs disponibles. De plus, nous expédions DDX3X Protéines (5) et DDX3X Kits (3) et beaucoup plus de produits pour cette protéine. Un total de 197 DDX3X produits sont actuellement listés.

Synonymes:: An3, D1Pas1-rs2, DBX, Ddx3, DDX3X, DDX14, Fin14, HLP2, pl10

afficher tous les anticorps	Gène	GeneID	UniProt
	DDX3X	1654	O00571
	DDX3X	13205	Q62167
	DDX3X	317335
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Human Polyclonal DDX3X Primary Antibody pour ICC, IF - ABIN152330 : Kang, Tsoi, Zhu, Su, Kay: Differential gene expression profiling in HELLP syndrome placentas. dans Reproductive sciences (Thousand Oaks, Calif.) 2008 (PubMed)
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Human Polyclonal DDX3X Primary Antibody pour ICC, IF - ABIN4304628 : Hagerstrand, Tong, Schumacher, Ilic, Shen, Cheung, Vazquez, Shrestha, Kim, Giacomelli, Rosenbluh, Schinzel, Spardy, Barbie, Mermel, Weir, Garraway, Tamayo, Mesirov, Beroukhim, Hahn: Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers. dans Cancer discovery 2013 (PubMed)
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Human Polyclonal DDX3X Primary Antibody pour IHC (p), ELISA - ABIN544111 : Franca, Belfiore, Spadari, Maga: Human DEAD-box ATPase DDX3 shows a relaxed nucleoside substrate specificity. dans Proteins 2007 (PubMed)
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Human Polyclonal DDX3X Primary Antibody pour IF, WB - ABIN541517 : Linder, Lasko, Ashburner, Leroy, Nielsen, Nishi, Schnier, Slonimski: Birth of the D-E-A-D box. dans Nature 1989 (PubMed)
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Human Polyclonal DDX3X Primary Antibody pour IF, WB - ABIN541518 : Lahn, Page: Functional coherence of the human Y chromosome. dans Science (New York, N.Y.) 1997 (PubMed)
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Human Monoclonal DDX3X Primary Antibody pour CyTOF, ELISA - ABIN4304633 : Sun, Wang, Lin, Zhao, Zhang, Yi, Sun, Chen, Jin: Proteome analysis of Duck Tembusu virus (DTMUV)-infected BHK-21 cells. dans Proteomics 2017 (PubMed)
Human Polyclonal DDX3X Primary Antibody pour ICC, ELISA - ABIN1002199 : Park, Lee, Kim, Song: Assignment of a human putative RNA helicase gene, DDX3, to human X chromosome bands p11.3-->p11.23. dans Cytogenetics and cell genetics 1998 (PubMed)
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Human Polyclonal DDX3X Primary Antibody pour ICC, ELISA - ABIN1002200 : Abdelhaleem: RNA helicases: regulators of differentiation. dans Clinical biochemistry 2005 (PubMed)
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Human Polyclonal DDX3X Primary Antibody pour IF, WB - ABIN2451947 : Sekiguchi, Iida, Fukumura, Nishimoto: Human DDX3Y, the Y-encoded isoform of RNA helicase DDX3, rescues a hamster temperature-sensitive ET24 mutant cell line with a DDX3X mutation. dans Experimental cell research 2004 (PubMed)

Plus d’anticorps contre DDX3X partenaires d’interaction

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) interaction partners

Study describes the structure of a DDX3X D1D2 core in complex with a 23-base pair dsRNA at pre-unwound state, revealing that two DDXs recognize a 2-turn dsRNA, each DDX mainly recognizes a single RNA strand, and conformational changes induced by ATP binding unwinds the RNA duplex in a cooperative manner.
Microarray analyses revealed that DDX3 is required for the expression of a set of pro-metastatic genes, including ATF4-modulated genes in an aggressive OSCC cell line. DDX3 activated translation of ATF4 and a set of its downstream targets, all of which contain upstream open reading frames (uORF)
showed that PeIF2alpha-mediated ATF4 mRNA translation requires DDX3 as a part of the eIF4F complex
The glycine-arginine domain in DDX3X mediates interaction with RNA G-quadruplexes -containing mRNAs.
DDX3X immunohistochemistry combined with hematoxylin and eosin staining may help differentiate atypical meningiomas from benign meningeal tumors
Evidence for a novel function of DDX3X in regulating expression and downstream functions of KLF4, a master negative regulator of the cell cycle in breast cancer.
Results suggest that DDX3 regulates epigenetic transcriptional and translational activation of p53 and colocalizes with p53 at centrosome during mitosis to ensure proper mitotic progression and genome stability, which supports the tumor-suppressive role of DDX3.
Data indicate that DEAD-box helicase 3 (DDX3) directly interacts with IkappaB kinase alpha (IKKalpha) and enhances its autophosphorylation and -activation.
DDX3X is a substrate of both HDAC6 catalytic domains.DDX3X is acetylated under specific stress conditions.
Mitogen-activated protein kinases and glycogen synthase kinase 3 phosphorylate Gle1A and thereby coordinate stress granule dynamics by altering DDX3 function.
DDX3X is required for full CK1 activity in living cells. Phosphorylation by CK1 impairs the ATPase activity of DDX3X and RNA destabilizes the DDX3X-CK1 complex.
the RNA helicase DDX3, is crucial in translation initiation of HIV-1 mRNA, but also fulfills an important role as RNA sensor and inducer of antiviral immunity in dendritic cells.
Our genetic and functional data suggest that partial loss of function of DDX3X can cause syndromic ID. The p.R79K allele affects a region of the protein outside the critical RNA helicase domain, offering a credible explanation for the observed retention of partial function, viability in hemizygous males, and lack of pathology in females
our study established DDX3 as a critical host interacting partner of the arenavirus nucleoprotein
an N-terminal conserved Nuclear Export Signal (NES) is required for export of human DDX3 from the nucleus, and identified three regions within DDX3 that can independently facilitate its nuclear import.
TRPV4 mediates Ca(2+) influx and nuclear accumulation of DDX3X in cells exposed to the Zika virus. Targeting of TRPV4 reduces infectivity of dengue, hepatitis C and Zika viruses. Our results highlight the role of TRPV4 in the regulation of DDX3X-dependent control of RNA metabolism and viral infectivity.
DDX3 regulates MTP gene expression and lipid homeostasis through interplay with HNF4 and SHP.
Through adopting the immunoprecipitation (IP), RNA immunoprecipitation (RIP), dual luciferase reporter assays, the authors illustrate that DDX3X could interact with Drosha/DGCR8 complex, elevate the processing activity of Drosha/DGCR8 complex on pri-miRNAs, and increase mature miRNA expression levels.
our study suggested that DDX3 prevents generation of cancer stem cells through epigenetically regulating a subset of tumor-suppressive miRNAs expressions, which strengthens tumor suppressor role of DDX3 in hepatocellular carcinoma.
this study shows that cancer-associated DDX3X mutations drive stress granule assembly and impair global translation

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) interaction partners

Ddx3x and Ddx3y are dispensable for spermatogenesis at least in mice. Unlike human, mice have an additional Ddx3y paralog D1pas1, that has been reported to be essential for spermatogenesis. Human and mouse DDX3 related proteins have distinct differences in their functions.
DDX3X is a substrate of both HDAC6 catalytic domains.DDX3X-intrinsically disordered region 1 is important for the stress granules formation.
Data provide further in vivo evidence for an essential contribution of a non-RLR DExD/H RNA helicase to innate immunity and suggest it may contribute to sex-related differences in resistance to microbes and resilience to inflammatory disease.
This study demonstrated that DDX3 regulates the translation of both Prkaca and Rac1 mRNAs in neurons and therefore maintains the PKA-Rac1 signaling axis at neurite terminals for both neurite outgrowth and dendritic spine formation.
Targeted Ddx3x ablation in the epiblast leads to widespread apoptosis and abnormal growth, which causes embryonic lethality in the Sox2-cre/+;Ddx3x(flox)/Y mutant around E11.5.These results have uncovered that mouse Ddx3x is essential for both embryo and extraembryonic development

DDX3X profil antigène

Antigen Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with DDX3X

DEAD-box helicase 3, X-linked (DDX3X) anticorps
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked (Ddx3x) anticorps
DEAD-box helicase 3, X-linked (Ddx3x) anticorps
DEAD-box helicase 3, X-linked L homeolog (ddx3x.L) anticorps
DEAD-box helicase 3, X-linked (ddx3x) anticorps

An3 anticorps
D1Pas1-rs2 anticorps
DBX anticorps
Ddx3 anticorps
DDX3X anticorps
DDX14 anticorps
Fin14 anticorps
HLP2 anticorps
pl10 anticorps

Protein level used designations for DDX3X

, , , , , , , , , , , , , , , , , , ATP-dependent RNA helicase DDX3X CAP-Rf DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked DEAD box protein 3, X-chromosomal DEAD box, X isoform DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 DEAD/H box-3 helicase like protein 2 helicase-like protein 2 D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 3 D1Pas1-related sequence 2 DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 3 DEAD box RNA helicase DEAD3 DEAD-box protein 3 (DEAD-box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1PAS1 related sequence 2) embryonic RNA helicase fibroblast growth factor inducible 14 mDEAD3 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked ATP-dependent RNA helicase DDX3X-like

GENE ID	SPECIES
1654	Homo sapiens
13205	Mus musculus
317335	Rattus norvegicus
379975	Xenopus laevis
418567	Gallus gallus
480886	Canis lupus familiaris
510093	Bos taurus
706891	Macaca mulatta
100028065	Monodelphis domestica
100082235	Ornithorhynchus anatinus
100348597	Oryctolagus cuniculus
100399667	Callithrix jacchus
100446823	Pongo abelii
100464548	Ailuropoda melanoleuca
100544480	Meleagris gallopavo
100555462	Anolis carolinensis
100731556	Cavia porcellus

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Show all anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) Anticorps with Pubmed References

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) interaction partners

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) interaction partners

Antigen Summary

Alternative names and synonyms associated with DDX3X

Protein level used designations for DDX3X