Aperçu des produits pour anti-Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1) Anticorps

Full name:: anti-Elongation Factor Tu GTP Binding Domain Containing 1 Anticorps (EFTUD1)

Chez www.anticorps-enligne.fr sont 23 Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1) Anticorps de 8 de différents fournisseurs disponibles. De plus, nous expédions et beaucoup plus de produits pour cette protéine. Un total de 28 Elongation Factor Tu GTP Binding Domain Containing 1 produits sont actuellement listés.

Synonymes:: 4932434J20Rik, 6030468D11Rik, AI451340, AU019507, AU022896, D7Ertd791e, FAM42A, HsT19294, RIA1

afficher tous les anticorps	Gène	GeneID	UniProt
	EFTUD1	79631	Q7Z2Z2
	EFTUD1	101592	Q8C0D5
	EFTUD1
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Plus d’anticorps contre Elongation Factor Tu GTP Binding Domain Containing 1 partenaires d’interaction

Human Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1) interaction partners

Mutations in EFL1 (Montrer EFNA1 Anticorps) clinically manifest phenotypes of infantile pancytopenia, exocrine pancreatic insufficiency and skeletal anomalies. Mutant EFL1 (Montrer EFNA1 Anticorps) proteins do not promote the release of yeast cytoplasmic Tif6 from the 60S subunit, likely preventing the formation of mature ribosomes.
Association of Elongation Factor-like 1 (EFL1 (Montrer EFNA1 Anticorps)) GTPase (Montrer RACGAP1 Anticorps) to SBDS (Montrer SBDS Anticorps) did not modify the affinity for GTP (Montrer AK3 Anticorps) but dramatically decreased that for GDP by increasing the dissociation rate of the nucleotide.
Upon EFL1 (Montrer EFNA1 Anticorps) binding, SBDS (Montrer SBDS Anticorps) is repositioned around helix 69, thus facilitating a conformational switch in EFL1 (Montrer EFNA1 Anticorps) that displaces eIF6 (Montrer EIF6 Anticorps) by competing for an overlapping binding site on the 60S ribosomal subunit.
Downregulation of EFTUD1 induced cell-cycle arrest and apoptosis in gliomas by impairing ribosome biogenesis

Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1) profil antigène

Antigen Summary

Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.

Alternative names and synonyms associated with Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1)

elongation factor like GTPase 1 (EFL1) anticorps
elongation factor like GPTase 1 (Efl1) anticorps

4932434J20Rik anticorps
6030468D11Rik anticorps
AI451340 anticorps
AU019507 anticorps
AU022896 anticorps
D7Ertd791e anticorps
FAM42A anticorps
HsT19294 anticorps
RIA1 anticorps

Protein level used designations for EFTUD1

elongation factor Tu GTP-binding domain-containing protein 1 , elongation factor-like 1 , ribosome assembly 1 homolog

GENE ID	SPECIES
79631	Homo sapiens
101592	Mus musculus

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