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Gemin6 is a component of the SMN (Montrer STMN1 Anticorps) complex that localizes to gems and interacts with several Sm proteins of the spliceosomal snRNPs.
Gemin8 (Montrer GEMIN8 Anticorps) has an essential role in the proper structural organization of the SMN (Montrer STMN1 Anticorps) complex and the involvement of the heteromeric subunit containing Gemin6, Gemin7 (Montrer GEMIN7 Anticorps), Gemin8 (Montrer GEMIN8 Anticorps), and Unrip (Montrer STRAP Anticorps) in the recruitment of Sm proteins to the snRNP (Montrer LSM2 Anticorps) assembly pathway
GEMIN6 is part of a large macromolecular complex, localized to both the cytoplasm and the nucleus, that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), GEMIN2 (SIP1\; MIM 602595), GEMIN3 (DDX20\; MIM 606168), GEMIN4 (MIM 606969), and GEMIN5 (MIM 607005).
, gem-associated protein 6
, gemin 6