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anti-Human Fibrillarin Anticorps:
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Caenorhabditis elegans (C. elegans) Monoclonal Fibrillarin Primary Antibody pour FACS, ICC - ABIN152610
Beyret, Lin: Pinpointing the expression of piRNAs and function of the PIWI protein subfamily during spermatogenesis in the mouse. dans Developmental biology 2011
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Cow (Bovine) Polyclonal Fibrillarin Primary Antibody pour IHC, WB - ABIN2778775
Bouwmeester, Bauch, Ruffner, Angrand, Bergamini, Croughton, Cruciat, Eberhard, Gagneur, Ghidelli, Hopf, Huhse, Mangano, Michon, Schirle, Schlegl, Schwab, Stein, Bauer, Casari, Drewes, Gavin, Jackson et al.: A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. ... dans Nature cell biology 2004
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Monoclonal Fibrillarin Primary Antibody pour IF, IHC (p) - ABIN534033
Aris, Blobel: Identification and characterization of a yeast nucleolar protein that is similar to a rat liver nucleolar protein. dans The Journal of cell biology 1988
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Yeast (Saccharomyces cerevisiae) Monoclonal Fibrillarin Primary Antibody pour IF, WB - ABIN361375
Langhendries, Nicolas, Doumont, Goldman, Lafontaine: The human box C/D snoRNAs U3 and U8 are required for pre-rRNA processing and tumorigenesis. dans Oncotarget 2018
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Human Polyclonal Fibrillarin Primary Antibody pour WB - ABIN1574130
Berkovits, Wolgemuth: The first bromodomain of the testis-specific double bromodomain protein Brdt is required for chromocenter organization that is modulated by genetic background. dans Developmental biology 2011
Mouse (Murine) Polyclonal Fibrillarin Primary Antibody pour IHC, WB - ABIN3021515
Zheng, Xiong, Wu, Chen, Chen, Fleming, Gao, Bi, Ge: Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells. dans Molecular & cellular proteomics : MCP 2015
Human Polyclonal Fibrillarin Primary Antibody pour ELISA, WB - ABIN4311650
Padilla, Uhart, Pacheco-Rodriguez, Peculis, Moss, Vaughan: Association of guanine nucleotide-exchange protein BIG1 in HepG2 cell nuclei with nucleolin, U3 snoRNA, and fibrillarin. dans Proceedings of the National Academy of Sciences of the United States of America 2008
Fibrillarin acts as a central node in a regulatory network engaged in imparting immunity against bacterial pathogens.
Nucleolar Methyltransferase Fibrillarin: Evolution of Structure and Functions.
FBL overexpression contributes to tumorigenesis and is associated with poor survival in patients with breast cancer.
NS1 protein of the human H3N2 virus interacts primarily via the C-terminal NLS2/NoLS and to a minor extent via the N-terminal NLS1 with the main nucleolar proteins, nucleolin, B23 and fibrillarin.
p32 is a new rRNA maturation factor involved in the remodeling from pre-90S particles to pre-40S and pre-60S particles that requires the exchange of FBL for Nop52.
Increased levels of exogenous BRAG2 in nucleoli result in redistribution of FBL to the nucleolar periphery.
Our data suggest that fibrillarin would play a critical role in the maintenance of nuclear shape and cellular growth.
Evidence that BIG1 and nucleolin, but not fibrillarin, can be present with p62 at the nuclear envelope confirms the presence of BIG1 and nucleolin in dynamic molecular complexes that change in composition while moving through nuclei
Data demonstrate that fibrillarin and Nop56 directly interact in vivo, and that this interaction is indispensable for the association of both proteins with the box C/D snoRNPs.
Fibrillin mutant Zebrafish embryos are hypomorphic, particularly for the brain and eye together with severe cellular hypoplasia and an impairment of neuronal differentiation and specification specifically in the dorsal midbrain and in retina
Analysis of the Localization of Fibrillarin and Sites of Pre-rRNA Synthesis in the Nucleolus-Like Bodies of Mouse GV Oocytes after Mild Treatment with Proteinase K
SUV39h1 associated with HP1 beta in fibrillarin-positive nucleolar regions.
Results suggest that proteasome-dependent processing of fibrillarin occurs upon mercury induction.
This splicing factor was more abundant in hepatocyte nuclei of mice fed genetically-modified soybeans than in control mice.
massive apoptosis was observed in early Fibrillarin(-/-) embryos, showing that fibrillarin is essential for development
This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.
34 kDa nucleolar scleroderma antigen
, 34-kD nucleolar scleroderma antigen
, RNA, U3 small nucleolar interacting protein 1
, rRNA 2'-O-methyltransferase fibrillarin
, nucleolar protein 1
, histone-glutamine methyltransferase