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Cow (Bovine) Polyclonal GBAS Primary Antibody pour WB - ABIN2783257
Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: The LIFEdb database in 2006. dans Nucleic acids research 2005
identified mitochondrial proteins 4-nitrophenylphosphatase domain and non-neuronal synaptosomal associated protein 25 (Montrer SNAP25 Anticorps)-like protein homolog (NIP (Montrer GIPC1 Anticorps)-SNAP)-1 (Montrer NIPSNAP3B Anticorps) and -2 as clarithromycin-binding proteins. Production of proinflammatory cytokines induced by lipopolysaccharides and Pam3-CSK4 in epithelial cell lines BEAS-2B and T24 were suppressed by knockdown of NIP (Montrer GIPC1 Anticorps)-SNAP-1 (Montrer NIPSNAP3B Anticorps) or -2
NIP (Montrer GIPC1 Anticorps)-SNAP-1 (Montrer NIPSNAP3B Anticorps) and -2 localized in the mitochondrial inner membrane space, whereas HSP60 (Montrer HSPD1 Anticorps) localized in the matrix. Expression levels of NIP (Montrer GIPC1 Anticorps)-SNAP-1 (Montrer NIPSNAP3B Anticorps) and -2 in cells were decreased by knockdown of HSP60 (Montrer HSPD1 Anticorps), but not HSP10 (Montrer HSPE1 Anticorps). The findings indicate that HSP60 (Montrer HSPD1 Anticorps) promotes folding and maintains the stability of NIP (Montrer GIPC1 Anticorps)-SNAP-1 (Montrer NIPSNAP3B Anticorps) and -2.
GBAS mutations could not explain phenotype of patients with combined oxidative phosphorylation system deficiencies.
CHCHD10 and GBAS are involved in oxidative phosphorylation.
This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. The encoded protein is localized to mitochondria and plays a role in oxidative phosphorylation. A pseudogene of this gene is located on the long arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
glioblastoma amplified sequence
, glioblastoma-amplified sequence
, protein NipSnap homolog 2
, 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like 2