SET Domain, Bifurcated 1 Produits
(SET Domain, Bifurcated 1 (SETDB1))
Catégories
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011].
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Catégories SET Domain, Bifurcated 1 en vedette
SET Domain, Bifurcated 1 Anticorps
High quality antibodies with extensive validation data.
SET Domain, Bifurcated 1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SET Domain, Bifurcated 1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
N° du produit
ABIN523280
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7155521
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Monkey, Mouse
Application
WB, ELISA, ICC
Validations
- (1)
- (2)
N° du produit
ABIN969394
Quantité
100 μL
Fiche technique
Fiche technique
SET Domain, Bifurcated 1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6204130
Quantité
96 tests
Fiche technique
Fiche technique
SET Domain, Bifurcated 1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1319683
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1319685
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3132280
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits SET Domain, Bifurcated 1
: "IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP." dans: eLife, Vol. 8, (2019) (PubMed).: "DNA CpG Methylation (5-Methylcytosine) and Its Derivative (5-Hydroxymethylcytosine) Alter Histone Posttranslational Modifications at the Pomc Promoter, Affecting the Impact of Perinatal Diet on ..." dans: Diabetes, Vol. 65, Issue 8, pp. 2258-67, (2016) (PubMed).
: "Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis." dans: Oncogene, Vol. 33, Issue 21, pp. 2807-13, (2014) (PubMed).
: "Silica nanoparticles induce cytokine responses in lung epithelial cells through activation of a p38/TACE/TGF-α/EGFR-pathway and NF-κΒ signalling." dans: Toxicology and applied pharmacology, Vol. 279, Issue 1, pp. 76-86, (2014) (PubMed).
: "The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset." dans: Nature, Vol. 471, Issue 7339, pp. 513-7, (2011) (PubMed).
: "Akt/PKB interacts with the histone H3 methyltransferase SETDB1 and coordinates to silence gene expression." dans: Molecular and cellular biochemistry, Vol. 305, Issue 1-2, pp. 35-44, (2007) (PubMed).
: "Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC." dans: Proteomics, Vol. 5, Issue 14, pp. 3589-99, (2005) (PubMed).
: "Transcriptional repression and heterochromatin formation by MBD1 and MCAF/AM family proteins." dans: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 13928-35, (2005) (PubMed).
: "Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly." dans: Molecular cell, Vol. 15, Issue 4, pp. 595-605, (2004) (PubMed).
: "mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression." dans: Molecular cell, Vol. 12, Issue 2, pp. 475-87, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à SET Domain, Bifurcated 1
SET domain bifurcated 1 (SETDB1), SET domain, bifurcated 1 (Setdb1), myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 (MLLT11), histone-lysine N-methyltransferase SETDB1 (LOC100120014), histone-lysine N-methyltransferase SETDB1 (LOC100461671), SET domain, bifurcated 1a (setdb1a), SET domain bifurcated 1 L homeolog (setdb1.L), SET domain bifurcated 1 (Setdb1), SET domain, bifurcated 1b (setdb1b), AU022152, ESET, fc07d03, H3-K9-HMTase4, im:7143091, KG1T, KMT1E, mKIAA0067, NV10069, SETDB1, si:ch211-81a5.6, TDRD21, wu:fa04a12, wu:fc07d03, wu:fj80h02, zgc:152899Protein level used designations for SET Domain, Bifurcated 1
- ERG-associated protein with SET domain
- ERG-associated protein with a SET domain, ESET
- H3-K9-HMTase 4
- histone H3-K9 methyltransferase 4
- histone-lysine N-methyltransferase SETDB1
- histone-lysine N-methyltransferase, H3lysine-9 specific 4
- lysine N-methyltransferase 1E
- tudor domain containing 21
- SET domain ERG-associated histone methyltransferase
- SET domain, bifurcated 1
- histone-lysine N-methyltransferase SETDB1-like
- histone-lysine N-methyltransferase SETDB1-A
- histone-lysine N-methyltransferase SETDB1-B
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