Coagulation Factor C Homolog, Cochlin (Limulus Polyphemus) ELISA Kit

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96 tests
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COCH Antigen Profile

Antigen Summary

The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated.

Alternative names and synonyms associated with COCH

  • cochlin (Coch) ELISA Kit
  • cochlin (COCH) ELISA Kit
  • AW122937 ELISA Kit
  • Coch-5B2 ELISA Kit
  • D12H14S564E ELISA Kit
  • COCH-5B2 ELISA Kit

Protein level used designations for COCH

coagulation factor C homolog (Limulus polyphemus) , coagulation factor C homolog, cochlin (Limulus polyphemus) , cochlin , Coch-5B2

362735 Rattus norvegicus
12810 Mus musculus
100174920 Cavia porcellus
504316 Bos taurus
395779 Gallus gallus
1690 Homo sapiens
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