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Envoyez-nous votre proposition de validation. J'aimerais valider ce produitRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Fournisseur | Clonality | References | Details |
---|---|---|---|---|---|---|---|---|---|---|
1 | ABIN5004550 | IF (p) | Alexa Fluor 750 | Rabbit | IgG | Chain A | Connectez-vous pour afficher | Polyclonal | 0 | |
1 | ABIN5004549 | IF (p) | Alexa Fluor 680 | Rabbit | IgG | Chain A | Connectez-vous pour afficher | Polyclonal | 0 |
General |
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Antigène | Hexosaminidase B (Beta Polypeptide) (HEXB) Anticorps |
Épitope | Chain A Alternatives |
Reactivité | Humain, Souris, Rat (Rattus) Alternatives |
Hôte | Lapin Alternatives |
Clonalité | |
Conjugué | Cet anticorp HEXB est conjugé à/à la Alexa Fluor 594 Alternatives |
Application |
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Alternatives
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Fournisseur | Connectez-vous pour afficher |
Détail du produit anti-HEXB anticorpsDétail du antigène HEXB Information d'application Stockage Images |
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Purification | Purified by Protein A. |
Immunogène | KLH conjugated synthetic peptide derived from human HEXB chain A |
Isotype | IgG |
Détail du antigène HEXBDétail du produit anti-HEXB anticorps Information d'application Stockage Images Haut de la page |
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Antigène | |
Autre désignation | HEXB (HEXB Antibody Extrait) |
Sujet |
Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq, Jul 2008]. Synonyms: Beta hexosaminidase beta chain, Beta hexosaminidase subunit beta, Beta N acetylhexosaminidase, Beta-hexosaminidase subunit beta chain A, Beta-N-acetylhexosaminidase subunit beta, Cervical cancer proto oncogene 7 protein, Cervical cancer proto-oncogene 7 protein, ENC 1AS, HCC 7, HCC-7, HCC7, HEX B, Hexb, HEXB_HUMAN, Hexosaminidase B beta polypeptide, Hexosaminidase B, Hexosaminidase subunit B, HexosaminidaseB, N acetyl beta glucosaminidase, N-acetyl-beta-glucosaminidase subunit beta, HEXB chain A. |
Pathways | Sensory Perception of Sound, Glycosaminoglycan Metabolic Process |
Information d'applicationDétail du produit anti-HEXB anticorps Détail du antigène HEXB Stockage Images Haut de la page |
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Indications d'application | IF(IHC-P) 1:50-200 |
Restrictions | For Research Use only |
StockageDétail du produit anti-HEXB anticorps Détail du antigène HEXB Information d'application Images Haut de la page |
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Format | Liquid |
Concentration | 1 μg/μL |
Buffer | Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide. |
Agent conservateur | Sodium azide |
Précaution d'utilisation | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Stock | 4 °C |
Stockage commentaire | Store at 4°C |
Date de péremption | 12 months |