Aperçu des produits pour anti-POU Domain, Class 3, Transcription Factor 4 (POU3F4) Anticorps

Full name:: anti-POU Domain, Class 3, Transcription Factor 4 Anticorps (POU3F4)

Chez www.anticorps-enligne.fr sont 10 POU Domain, Class 3, Transcription Factor 4 (POU3F4) Anticorps de 9 de différents fournisseurs disponibles. De plus, nous expédions POU Domain, Class 3, Transcription Factor 4 Protéines (8) et POU Domain, Class 3, Transcription Factor 4 Kits (5) et beaucoup plus de produits pour cette protéine. Un total de 25 POU Domain, Class 3, Transcription Factor 4 produits sont actuellement listés.

Synonymes:: Brain-4, Brn-4, Brn4, DFN3, DFNX2, oct-9, OTF-9, Otf9, POU 2, pou2, pou3f4-a, RHS2, Slf, XlPOU-2, XlPOU2

afficher tous les anticorps	Gène	GeneID	UniProt
	POU3F4	5456	P49335
	POU3F4	29589	P62516
	POU3F4	18994	P62515
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Pathways pertinentes pour anti-POU Domain, Class 3, Transcription Factor 4 Anticorps

Sensory Perception of Sound

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anti-POU Domain, Class 3, Transcription Factor 4 Anticorps mieux référencés

Cow (Bovine) Polyclonal POU3F4 Primary Antibody pour WB - ABIN2792648 : Xia, Kikuchi, Minowa, Katori, Oshima, Noda, Ikeda: Late-onset hearing loss in a mouse model of DFN3 non-syndromic deafness: morphologic and immunohistochemical analyses. dans Hearing research 2002 (PubMed)
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Human Polyclonal POU3F4 Primary Antibody pour IHC, IHC (p) - ABIN4285272 : Diaz-de-Durana, Lau, Knee, Filippi, Londei, McNamara, Nasoff, DiDonato, Glynne, Herman: IL-2 immunotherapy reveals potential for innate beta cell regeneration in the non-obese diabetic mouse model of autoimmune diabetes. dans PLoS ONE 2013 (PubMed)

Plus d’anticorps contre POU Domain, Class 3, Transcription Factor 4 partenaires d’interaction

Human POU Domain, Class 3, Transcription Factor 4 (POU3F4) interaction partners

POU3F4 mutations can be predicted by incomplete partition type III anomaly by radiological examination of the inner ear. All six of the patients showed mixed hearing loss, but none showed fluctuations in hearing, which may be related to the lack of vestibular aqueduct enlargement at the operculum.
Sequencing of the entire POU3F4 gene is recommended in patients with characteristic temporal bone malformations. Results of POU3F4 mutation testing are important not only for a proper genetic counseling, but also for adequate preparation and conduction of a surgical procedure.
A nonsense mutation is identified in a family displaying the pedigree consistent with X-linked recessive pattern in POU3F4 gene.
POU3F4 mutation in profoundly deaf patients may have poorer prognosis after cochlear implantation, than other types.
findings may greatly contribute to the elucidation of the roles of the Oct (Montrer Plxna2 Anticorps) and Myc (Montrer MYC Anticorps) proteins in osteoblast direct reprogramming. The results may also lead to establishment of novel regenerative therapy for various bone resorption diseases
Audiological, medical, and family histories were collected and family members interviewed to compare hearing thresholds and case histories between cases with mutations in SMPX (Montrer SMPX Anticorps) versus POU3F4.
Our data suggest that different POU3F4 mutations might show different recurrence rate in siblings of the incomplete partition type III anomaly especially in East Asian population
POU3F4 mutations are associated with X-linked deafness
We concluded that the probable presence of the third window effect is not limited to the particular type of POU3F4 mutation.
Results show three novel mutations in the POU3F4 gene resulting in profound hearing loss in both humans and mice.

Xenopus laevis POU Domain, Class 3, Transcription Factor 4 (POU3F4) interaction partners

pou3f4 expression in inner ear might be under the control of distinct regulatory elements that fine-tune the spatio-temporal activity of this gene

Mouse (Murine) POU Domain, Class 3, Transcription Factor 4 (POU3F4) interaction partners

Brn4 substantially contributes to cochlear gap junction properties to maintain the proper EP in cochleae, similar to connexin-related deafness.
Efnb2 (Montrer EFNB2 Anticorps) expression was attenuated in Pou3f4 hemizygous null mutants relative to control.
Results show three novel mutations in the POU3F4 gene resulting in profound hearing loss in both humans and mice.
This study indicated a model whereby Pou3f4 in the otic mesenchyme establishes an Eph/ephrin-mediated fasciculation signal that promotes inner radial bundle formation.
pou3f4 expression in inner ear might be under the control of distinct regulatory elements that fine-tune the spatio-temporal activity of this gene
The effects of Brn-4 on the neuronal differentiation and development of neural stem cells, were investigated.
a transcription factor targeted to the early mouse pancreas induces ectopic glucagon (Montrer GCG Anticorps) gene expression
late-onset effect of Brn-4 deficiency on the hearing organ of the mouse. About one third of heterozygous female mice revealed late-onset profound deafness at the age of 1 year.
lack of role in regulating Pax6 (Montrer PAX6 Anticorps) and Nkx2.2 (Montrer Nkx2-2 Anticorps)
Tbx1 (Montrer TBX1 Anticorps) and Brn4 function in signaling from the periotic mesenchyme to the otic vesicle to direct proper coiling of the cochlear duct.

POU Domain, Class 3, Transcription Factor 4 (POU3F4) profil antigène

Antigen Summary

This gene encodes a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness.

Alternative names and synonyms associated with POU Domain, Class 3, Transcription Factor 4 (POU3F4)

POU class 3 homeobox 4 (POU3F4) anticorps
POU class 3 homeobox 4 (pou3f4) anticorps
POU class 3 homeobox 4 L homeolog (pou3f4.L) anticorps
POU class 3 homeobox 4 (Pou3f4) anticorps
POU domain, class 3, transcription factor 4 (Pou3f4) anticorps

Brain-4 anticorps
Brn-4 anticorps
Brn4 anticorps
DFN3 anticorps
DFNX2 anticorps
oct-9 anticorps
OTF-9 anticorps
Otf9 anticorps
POU 2 anticorps
pou2 anticorps
pou3f4-a anticorps
RHS2 anticorps
Slf anticorps
XlPOU-2 anticorps
XlPOU2 anticorps

Protein level used designations for POU3F4

, , , , , , , , , , , , , , , , , , , POU domain, class 3, transcription factor 4 POU class 3 homeobox 4 POU domain, class 3, transcription factor 4-like brain-specific homeobox/POU domain protein 4 octamer-binding transcription factor 9 POU 2 transcription factor POU domain, class 3, transcription factor 4-A Transcription factor POU2 XLPOU 2 xlPOU2 OTF-9 RHS2 class III POU protein brain-4 brn-4 oct-9 octamer-binding protein 9 Brain-specific homeobox/POU domain protein 4 POU homeodomain protein brain-4 class III POU-domain protein sex linked fidget

GENE ID	SPECIES
539732	Bos taurus
100152446	Sus scrofa
100036711	Xenopus (Silurana) tropicalis
100472065	Ailuropoda melanoleuca
5456	Homo sapiens
397929	Xenopus laevis
491988	Canis lupus familiaris
29589	Rattus norvegicus
101829289	Mesocricetus auratus
18994	Mus musculus

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