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anti-Human NRP2 Anticorps:
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Human Polyclonal NRP2 Primary Antibody pour BR, CyTOF - ABIN5012962
Fassold, Falk, Anders, Hirsch, Mirsky, Straub: Soluble neuropilin-2, a nerve repellent receptor, is increased in rheumatoid arthritis synovium and aggravates sympathetic fiber repulsion and arthritis. dans Arthritis and rheumatism 2009
Show all 11 Pubmed References
Cow (Bovine) Polyclonal NRP2 Primary Antibody pour IHC, ELISA - ABIN1582215
Hey-Cunningham, Markham, Fraser, Berbic: Dysregulation of vascular endothelial growth factors and their neuropilin receptors in the eutopic endometrium of women with endometriosis. dans Reproductive sciences (Thousand Oaks, Calif.) 2013
Human Polyclonal NRP2 Primary Antibody pour IHC, IHC (p) - ABIN4338865
Fonseca, Bingle, Santos-Silva, Lopes, de Almeida, de Andrade, Mariano, Kowalski, Rangel, Martins, Meurer, Speight, Vargas: Semaphorins and neuropilins expression in salivary gland tumors. dans Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2016
Human Polyclonal NRP2 Primary Antibody pour WB - ABIN442214
Roth, Agemy, Kotamraju, Braun, Teesalu, Sugahara, Hamzah, Ruoslahti: Transtumoral targeting enabled by a novel neuropilin-binding peptide. dans Oncogene 2012
Human Monoclonal NRP2 Primary Antibody pour CyTOF, FACS - ABIN4899777
Jaalouk, Ozawa, Sun, Lahdenranta, Schlingemann, Pasqualini, Arap: The original Pathologische Anatomie Leiden-Endothelium monoclonal antibody recognizes a vascular endothelial growth factor binding site within neuropilin-1. dans Cancer research 2007
Human Polyclonal NRP2 Primary Antibody pour WB - ABIN655525
Davare, Lal, Peckham, Prajapati, Gultekin, Rubin, Keller: Secreted meningeal chemokines, but not VEGFA, modulate the migratory properties of medulloblastoma cells. dans Biochemical and biophysical research communications 2014
The authors also identified single-nucleotide polymorphisms in NRP2 (Montrer NELL2 Anticorps) and IGFBP4 (Montrer IGFBP4 Anticorps) loci that increase and reduce risk of lichen planus in hepatitis C virus-infected patients, respectively.
Authors found that NRP2 (Montrer NELL2 Anticorps) gene silencing in metastatic melanoma cell lines inhibited tumor cell growth in vitro; furthermore, knockdown of NRP2 (Montrer NELL2 Anticorps) expression in the metastatic melanoma cell line 1205Lu significantly inhibited in-vivo tumor growth and metastasis.
Study identifies NRP2 (Montrer NELL2 Anticorps) and ESL-1 (Montrer GLG1 Anticorps) as targets for polysialylation in murine microglia and human THP-1 (Montrer GLI2 Anticorps) macrophages and reveals a striking convergence in the regulation of the two polysialylated acceptors in the course of inflammatory activation. A pool of polysialylated NRP2 (Montrer NELL2 Anticorps) and ESL-1 (Montrer GLG1 Anticorps) is assembled after injury or in culture and its shedding is an early response to lipopolysaccharide-induced activation of microglia.
Neuropilin 2 isoform NRP2b contributed to the oncogenic response to transforming growth factor-beta (TGFbeta (Montrer TGFB1 Anticorps)) and correlated with tumor progression in non-small cell lung cancer (NSCLC) patients.
Sema3a (Montrer SEMA3A Anticorps)-Nrp2 (Montrer NELL2 Anticorps) signaling along an unrecognized pancreatic developmental axis constitutes a chemoattractant system essential for generating the hallmark morphogenetic properties of pancreatic islets.
NRP2 (Montrer NELL2 Anticorps) promotes tumourigenesis and metastasis in Oesophageal squamous cell carcinoma (ESCC) through deregulation of ERK-MAPK (Montrer MAPK1 Anticorps)-ETV4 (Montrer ETV4 Anticorps)-MMP-E-cadherin (Montrer CDH1 Anticorps) signalling.
The summarizes the structure and function features of pathway-related molecules of VEGFC (Montrer VEGFC Anticorps)/D-VEGFR3 (Montrer FLT4 Anticorps)/NRP2 (Montrer NELL2 Anticorps) axis, stages of various tumors and their molecular mechanisms and significances in tuthe expression changes of these molecules in different anatomic organs or histopathologic types or development lymphatic metastasis.
NRP2 (Montrer NELL2 Anticorps) inhibits WDFY1 (Montrer WDFY1 Anticorps) transcription by preventing the nuclear localization of a transcription factor, Fetal ALZ50-reactive clone 1 (FAC1 (Montrer BPTF Anticorps)).
Sequence Requirements for Neuropilin-2 Recognition by ST8SiaIV (Montrer ST8SIA4 Anticorps) and Polysialylation of Its O-Glycans.
the concurrent high expression of VEGF-C (Montrer VEGFC Anticorps) and NRP2 (Montrer NELL2 Anticorps) is predictive of the unfavorable prognosis in glioblastoma.
data suggest that Sema3f (Montrer SEMA3F Anticorps) and Nrp2 are dispensable for the exclusion of vessels from the cap mesenchyme during kidney development.
Study identifies NRP2 and ESL-1 (Montrer GLG1 Anticorps) as targets for polysialylation in murine microglia and human THP-1 (Montrer GLI2 Anticorps) macrophages and reveals a striking convergence in the regulation of the two polysialylated acceptors in the course of inflammatory activation. A pool of polysialylated NRP2 and ESL-1 (Montrer GLG1 Anticorps) is assembled after injury or in culture and its shedding is an early response to lipopolysaccharide-induced activation of microglia.
Sema3F (Montrer SEMA3F Anticorps)-Npn-2/PlexA3 (Montrer PLXNA3 Anticorps) signaling is essential for cell surface AMPAR homeostatic downscaling in response to an increase in neuronal activity, Npn-2 associates with AMPA (Montrer GRIA3 Anticorps)-type glutamate (Montrer GRIN1 Anticorps) receptors
Sema3G (Montrer SEMA3G Anticorps) induces cell collapse in an Nrp2/PlexinD1-dependent manner.
Sema3a (Montrer SEMA3A Anticorps)-Nrp2 signaling along an unrecognized pancreatic developmental axis constitutes a chemoattractant system essential for generating the hallmark morphogenetic properties of pancreatic islets.
Nrp2 deficiency increased blood vessel permeability and decreased lymphatic vessel drainage during inflammation, highlighting the importance of the NRP2/SEMA3F (Montrer SEMA3F Anticorps) pathway in the modulation of tissue swelling and resolution of postinflammatory edema.
These results point to a new role for NRP2 in the positioning of neurons during adult hippocampal neurogenesis, acting via the GSK3beta signaling pathway.
The authors demonstrate that expression of Semaphorin-3F (Montrer SEMA3F Anticorps) in the outer hair cell region inhibits type I spiral ganglion neuron process extension by activating Neuropilin-2 receptors expressed on spiral ganglion neurons.
neuropilin-2 is developmentally regulated.
Data show that Chicken ovalbumin upstream promoter transcription factor (Montrer NR2F1 Anticorps) II (COUP-TFII (Montrer NR2F2 Anticorps))-induced expression of Neuropilin-2 (Nrp2) and its down-regulation control the destination of preoptic area (POa)-derived GABAergic neurons.
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C and SEMA3F protein sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
, receptor for VEGF165 and semaphorins class3
, vascular endothelial cell growth factor 165 receptor 2