Profil protéine

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Alternative names and synonyms associated with BAD

• BCL2-associated agonist of cell death b (badb) anticorps
• BCL2 associated agonist of cell death (BAD) anticorps
• BCL2-associated agonist of cell death (Bad) anticorps

• AI325008 anticorps
• BAD anticorps
• Bbc2 anticorps
• BCL2L8 anticorps
• fa01b12 anticorps
• Afficher tous les alias de synonymes
• wu:fa01b12 anticorps
• wu:fa96d04 anticorps

Protein level used designations for BAD

proapoptotic BH3-only protein , BCL2-antagonist of cell death , BCL2-associated agonist of cell death , BCL-X/BCL-2 binding protein , BCL2-antagonist of cell death protein , BCL2-binding component 6 , BCL2-binding protein , bcl-2-binding component 6 , bcl-2-like protein 8 , bcl-XL/Bcl-2-associated death promoter , bcl2 antagonist of cell death , bcl2-L-8 , Bcl-associated death promoter , bcl-xL/Bcl-2-associated death promoter , Bcl2-antagonist of cell death , bcl-2 associated death agonist , bcl2-associated death promoter