anti-Humain HSPB1 anticorps pour Immunohistochemistry (Paraffin-embedded Sections)

Recommended HSPB1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Heat Shock 27kDa Protein 1 (HSPB1) Anticorps
  • CMT2F
  • HMN2B
  • HS.76067
  • HSP27
  • HSP28
  • Hsp25
  • SRP27
  • 27kDa
  • Hsp27
  • cb153
  • cb660
  • hsp1
  • hsp25
  • hsp27
  • id:ibd2821
  • sb:cb660
  • zgc:103437
  • HSPB1
  • cmt2f
  • hs.76067
  • hsp28
  • heat shock protein family B (small) member 1
  • heat shock protein 1
  • heat shock protein, alpha-crystallin-related, 1
  • heat shock protein family B (small) member 1 L homeolog
  • HSPB1
  • Hspb1
  • hspb1
  • hspb1.L
Épitope
AA 100-150
85
72
55
45
22
15
13
13
10
10
10
10
6
6
5
5
5
5
5
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
825
276
271
96
85
71
68
66
36
30
29
26
18
11
11
9
6
3
2
2
2
2
1
1
1
Hôte
Lapin
502
341
2
Clonalité
Polyclonal
Conjugué
Cet anticorp HSPB1 est non-conjugé
34
33
23
22
19
13
13
13
11
11
10
10
10
10
10
9
9
9
5
5
5
5
5
5
5
5
5
4
4
3
3
3
3
3
3
3
3
3
3
3
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
714
327
270
265
228
212
169
157
59
39
17
14
11
8
6
4
2
2
1
1
1
Options
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N° du produit ABIN672441
$ 318.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
12.623349 ABIN4319982 IHC IHC (p) WB Rabbit IgG Connectez-vous pour afficher Polyclonal 1
12.623349 ABIN4319981 IHC IHC (p) Rabbit IgG Connectez-vous pour afficher Polyclonal 2
12.623349 ABIN316084 IHC (p) IHC ELISA WB Mouse IgG1 AA 1-205 Connectez-vous pour afficher 2A5
12.623349 ABIN410085 ICC IF IHC (p) IP IHC WB Mouse IgG1 kappa Connectez-vous pour afficher 8A7
12.623349 ABIN4319992 ICC IF IHC IHC (p) IP WB Rabbit IgG Center Connectez-vous pour afficher Polyclonal
12.623349 ABIN743138 IF (p) IHC (p) WB Rabbit IgG pSer15 Connectez-vous pour afficher Polyclonal
12.623349 ABIN5611604 EIA IHC (p) WB Rabbit IgG Connectez-vous pour afficher Polyclonal
12.623349 ABIN498848 IHC (p) Rabbit pSer78, pSer82 Connectez-vous pour afficher Polyclonal
12.623349 ABIN498746 IHC (p) WB Rabbit pSer82 Connectez-vous pour afficher Polyclonal
12.623349 ABIN4320006 IHC (p) WB Rabbit Connectez-vous pour afficher Polyclonal
12.623349 ABIN4319975 IHC IHC (p) WB Rabbit pSer82 Connectez-vous pour afficher Polyclonal
12.623349 ABIN498626 IHC (p) WB Rabbit Connectez-vous pour afficher Polyclonal
12.623349 ABIN1107613 IHC (p) WB Rabbit IgG C-Term Connectez-vous pour afficher Polyclonal
12.623349 ABIN498463 IHC (p) WB Rabbit Connectez-vous pour afficher Polyclonal
12.623349 ABIN364326 IHC (p) ELISA WB Mouse IgG1 AA 1-205 Connectez-vous pour afficher 2A5
12.623349 ABIN214359 ICC IHC (p) IP ELISA WB Mouse IgG1, lambda Connectez-vous pour afficher
12.623349 ABIN4319972 IHC IHC (p) WB Rabbit Connectez-vous pour afficher Polyclonal
12.623349 ABIN615155 IHC (p) IP WB Rabbit Connectez-vous pour afficher Polyclonal
12.623349 ABIN498937 IHC (p) Rabbit Connectez-vous pour afficher Polyclonal
1 ABIN391300 IHC (p) WB Rabbit Ig Fraction AA 108-136, Center Connectez-vous pour afficher Polyclonal 2

General

Antigène Heat Shock 27kDa Protein 1 (HSPB1) Anticorps
Épitope AA 100-150
(85), (72), (55), (45), (22), (15), (13), (13), (10), (10), (10), (10), (6), (6), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(825), (276), (271), (96), (85), (71), (68), (66), (36), (30), (29), (26), (18), (11), (11), (9), (6), (3), (2), (2), (2), (2), (1), (1), (1)
Hôte Lapin
(502), (341), (2)
Clonalité
Polyclonal
Conjugué Cet anticorp HSPB1 est non-conjugé
(34), (33), (23), (22), (19), (13), (13), (13), (11), (11), (10), (10), (10), (10), (10), (9), (9), (9), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(714), (327), (270), (265), (228), (212), (169), (157), (59), (39), (17), (14), (11), (8), (6), (4), (2), (2), (1), (1), (1)
Pubmed 2 références disponible
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Détail du produit anti-HSPB1 anticorps

Détail du antigène HSPB1 Information d'application Stockage References for anti-HSPB1 antibody (ABIN672441) Images
Purification Purified by Protein A.
Immunogène KLH conjugated synthetic peptide derived from human HSP27
Isotype IgG

Détail du antigène HSPB1

Détail du produit anti-HSPB1 anticorps Information d'application Stockage References for anti-HSPB1 antibody (ABIN672441) Images Haut de la page
Antigène
Autre désignation HSP27 (HSPB1 Antibody Extrait)
Sujet

Heat Shock Protein 27 (HSP27) is a 27 kDa member of a family of proteins whose expression and function are stimulated by heat shock and other stress stimuli. A major function of these proteins is to serve as chaperones that bind to and stabilize the active conformation of other proteins. HSP27, along with other members of the small HSP group, possesses a C-terminal Alpha-crystalline homology domain. HSP27 is localized to the cytoplasm of unstressed cells but can redistribute to the nucleus in response to stress, where it may function to stabilize DNA and/or the nuclear membrane. Cytoplasmic HSP27 exists in multiple complexes. One complex consists of HSP27, Akt (PKB), MAPKAP-kinase 2, and p38 MAPK. The presence of HSP27 in this complex is required for Akt activation by stress stimuli. Another complex consists of HSP27 and the IKK complex. HSP27 is also an actin capping protein that binds to the barbed (growing) ends of actin filaments, thereby inhibiting filament extension. Phosphorylation of HSP27 on serine 82 by MAPKAP-kinase 2 leads to HSP27 dissociation from the Akt/MAPKAP-kinase 2/p38 complex and from actin filaments, and stimulates HSP27 binding to the IKK complex.

Subcellular location: Cytoplasm, Nucleus

Synonyms: CMT2F, HMN2B, HSP27, HSP28, Hsp25, SRP27, HS.7667, HEL-S-12, Heat shock protein beta-1, HspB1, 28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, HSP 27, Stress-responsive protein 27

ID gène 3315
UniProt P04792
Domaine de recherche Heat Shock Proteins
Pathways Signalisation MAPK, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling

Information d'application

Détail du produit anti-HSPB1 anticorps Détail du antigène HSPB1 Stockage References for anti-HSPB1 antibody (ABIN672441) Images Haut de la page
Indications d'application WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Stockage

Détail du produit anti-HSPB1 anticorps Détail du antigène HSPB1 Information d'application References for anti-HSPB1 antibody (ABIN672441) Images Haut de la page
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20°C
Date de péremption 12 months

References for anti-HSPB1 antibody (ABIN672441)

Détail du produit anti-HSPB1 anticorps Détail du antigène HSPB1 Information d'application Stockage Images Haut de la page
Produit citée dans:

Gao, Liu, Chen, Lv, Wu, Mi, Wang: "Comparative study of Hsp27, GSK3?, Wnt1 and PRDX3 in Hirschsprung's disease." dans: International journal of experimental pathology, Vol. 95, Issue 3, pp. 229-37, 2014

Wang, Yang, Liu, Zhou, Wu, Qiao, Li, Wang: "Dietary supplementation with the probiotic Lactobacillus fermentum I5007 and the antibiotic aureomycin differentially affects the small intestinal proteomes of weanling piglets." dans: The Journal of nutrition, Vol. 142, Issue 1, pp. 7-13, 2011

Images

Détail du produit anti-HSPB1 anticorps Détail du antigène HSPB1 Information d'application Stockage References for anti-HSPB1 antibody (ABIN672441) Haut de la page
Supplier Images
Immunohistochemistry (IHC) image for anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 100-150) antibody (ABIN672441) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-HSP27/HspB1/H...
Immunohistochemistry (IHC) image for anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 100-150) antibody (ABIN672441) Formalin-fixed and paraffin embedded rat brain labeled with (ABIN672441) Rabbit Ant...
SDS-PAGE (SDS) image for anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 100-150) antibody (ABIN672441) L1 mouse brain lysates L2 mouse liver lysates probed with Anti HSP27/HspB1/HSP25 Poly...
Immunofluorescence (IF) image for anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 100-150) antibody (ABIN672441) Formalin-fixed and paraffin-embedded rat brain labeled with Anti-HSP27/HspB1/HSP25 Po...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Heat Shock 27kDa Protein 1 (HSPB1) (AA 100-150) antibody (ABIN672441) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-HSP27/HspB1/H...