anti-Singe HSPB1 anticorps pour Immunofluorescence

Recommended HSPB1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Heat Shock 27kDa Protein 1 (HSPB1) Anticorps
  • CMT2F
  • HMN2B
  • HS.76067
  • HSP27
  • HSP28
  • Hsp25
  • SRP27
  • 27kDa
  • Hsp27
  • cb153
  • cb660
  • hsp1
  • hsp25
  • hsp27
  • id:ibd2821
  • sb:cb660
  • zgc:103437
  • HSPB1
  • cmt2f
  • hs.76067
  • hsp28
  • heat shock protein family B (small) member 1
  • heat shock protein 1
  • heat shock protein, alpha-crystallin-related, 1
  • heat shock protein family B (small) member 1 L homeolog
  • HSPB1
  • Hspb1
  • hspb1
  • hspb1.L
Reactivité
Humain, Singe
825
277
272
96
85
71
68
66
35
30
29
26
18
11
11
9
6
3
2
2
2
2
1
1
1
Hôte
Lapin
502
341
2
Clonalité
Polyclonal
Conjugué
Cet anticorp HSPB1 est non-conjugé
34
33
23
22
19
13
13
13
11
11
10
10
10
10
10
9
9
9
5
5
5
5
5
5
5
5
5
4
4
3
3
3
3
3
3
3
3
3
3
3
2
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
714
327
270
266
227
212
168
157
59
40
17
14
11
8
6
4
2
2
1
1
1
Options
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N° du produit ABIN222927
$ 295.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN127002 IF IP WB Rabbit Connectez-vous pour afficher Polyclonal
1 ABIN2622163 IF IHC WB Rabbit pSer15 Connectez-vous pour afficher Polyclonal
1 ABIN220304 ICC IF IHC (p) ELISA WB Mouse IgG1 Connectez-vous pour afficher
1 ABIN1002408 IF IP WB Rabbit IgG Connectez-vous pour afficher Polyclonal
1 ABIN215209 ICC IF IP IHC ELISA WB Mouse IgG1 Connectez-vous pour afficher
1 ABIN241651 ICC IF IP ELISA WB Rabbit Connectez-vous pour afficher Polyclonal

General

Antigène Heat Shock 27kDa Protein 1 (HSPB1) Anticorps
Reactivité Humain, Singe
(825), (277), (272), (96), (85), (71), (68), (66), (35), (30), (29), (26), (18), (11), (11), (9), (6), (3), (2), (2), (2), (2), (1), (1), (1)
Hôte Lapin
(502), (341), (2)
Clonalité
Polyclonal
Conjugué Cet anticorp HSPB1 est non-conjugé
(34), (33), (23), (22), (19), (13), (13), (13), (11), (11), (10), (10), (10), (10), (10), (9), (9), (9), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(714), (327), (270), (266), (227), (212), (168), (157), (59), (40), (17), (14), (11), (8), (6), (4), (2), (2), (1), (1), (1)
Pubmed 1 référence disponible
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Détail du produit anti-HSPB1 anticorps

Détail du antigène HSPB1 Information d'application Stockage References for anti-HSPB1 antibody (ABIN222927) Images
Specificité The antibody detects a 27 kDa protein, corresponding to the apparent molecular mass of Hsp27 on SDS-PAGE immunoblots, in samples from human, monkey, dog (weakly) and pig (weakly) origins.
Purification Affinity purified
Immunogène Recombinant human Hsp27
Isotype IgG

Détail du antigène HSPB1

Détail du produit anti-HSPB1 anticorps Information d'application Stockage References for anti-HSPB1 antibody (ABIN222927) Images Haut de la page
Antigène
Autre désignation Hsp27 (HSPB1 Antibody Extrait)
Sujet Human Hsp27, mouse Hsp25 and αβ-crystallin are part of a diverse family of small heat shock proteins which are produced in all organisms. They function as chaperone-like proteins by binding unfolded polypeptides and preventing uncontrolled protein aggregation. Hsp27 is believed to exist mainly as oligomers of as many as 8-40 Hsp27 protein monomers in cells and data sμggests that the large oligomers of Hsp27 have a chaperone-like activity by serving as a site where unfolding proteins may bind until ATP and Hsp70-dependent refolding can occur. Hsp27 is believed to protect cells by enhancing cellular glutathione levels and elevated glutathione levels have been measured in cells overexpressing Hsp27. Data from studies using wild-type Hsp27 and mutant forms in which the serine phosphorylation sites were mutated to alanines, glycines or aspartates, have shown that cellular glutathione levels depend on the oligomerization of Hsp27. Recent findings indicate that Hsp27 is also a negative regulator of cytochrome c-dependent activation of procaspase-3.
Synonyms: HSPB1, CMT2F, DKFZp586P1322, HS.76067, HSP27, HSP28, Hsp25
ID gène 11036357
Domaine de recherche Cardiovascular, Contractility, Atherosclerosis, Heat Shock Proteins, Cytoskeleton, Microfilaments
Pathways Signalisation MAPK, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling

Information d'application

Détail du produit anti-HSPB1 anticorps Détail du antigène HSPB1 Stockage References for anti-HSPB1 antibody (ABIN222927) Images Haut de la page
Indications d'application Western blotting (1-2 μg/mL), immunoprecipitation (5-10 μg/mL), immunocytochemistry (10-15 μg/mL), and ELISA (1 μg/mL). However, the optimal conditions should be determined individually. The antibody detects a 27 kDa protein, corresponding to the apparent molecular mass of Hsp27 on SDS-PAGE immunoblots, in samples from human, monkey, dog (weakly) and pig (weakly) origins.
Restrictions For Research Use only

Stockage

Détail du produit anti-HSPB1 anticorps Détail du antigène HSPB1 Information d'application References for anti-HSPB1 antibody (ABIN222927) Images Haut de la page
Format Liquid
Concentration 0.2 mg/mL
Buffer 100 μg (200 μg/mL) in phosphate buffered saline (PBS), pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal.
Agent conservateur Thimerosal (Merthiolate)
Précaution d'utilisation This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation The antibody solution should be gently mixed before use.
Stock -20 °C
Stockage commentaire For long-term storage, aliquot and freeze at -70 °C.
Date de péremption 12 months

References for anti-HSPB1 antibody (ABIN222927)

Détail du produit anti-HSPB1 anticorps Détail du antigène HSPB1 Information d'application Stockage Images Haut de la page
Produit citée dans:

Cheng, Pollock, Mahimkar, Olson, Lovett: "Matrix metalloproteinase 2 and basement membrane integrity: a unifying mechanism for progressive renal injury." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 11, pp. 1898-900, 2006