Aperçu des produits pour anti-MAPK3 (MAPK3) Anticorps

Human Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

1. intact keratin filaments are regulators for PKB/Akt (Montrer AKT1 Anticorps) and p44 (Montrer GTF2H2 Anticorps)/42 activity, basal and in response to stretch.

2. Immune profiling of human prostate epithelial cells in health and pathology determined by expression of p38 (Montrer CRK Anticorps)/TRAF-6 (Montrer TRAF6 Anticorps)/ERK (Montrer EPHB2 Anticorps) MAP kinases pathways has been reported.

3. Integrated ERK1/ERK2 (Montrer MAPK1 Anticorps) response to B (Montrer TDO2 Anticorps)-cell receptor stimulation and SF3B1 (Montrer SF3B2 Anticorps) gene mutations refine prognosis in chronic lymphocytic leukemia.

4. These findings identified the relationship between ERK1/2 Snitrosylation and phosphorylation.

5. A cellular threshold for active ERK1/2 levels determines Raf (Montrer RAF1 Anticorps)/MEK (Montrer MAP2K1 Anticorps)/ERK (Montrer EPHB2 Anticorps)-mediated growth arrest versus death responses.

6. ERK1/2/p53 (Montrer TP53 Anticorps)/PUMA (Montrer BBC3 Anticorps) signaling axis is related to cisplatin-induced cell death in ovarian cancer cells.

7. results demonstrated that OEA exerts anti-inflammatory effects by enhancing PPARalpha (Montrer PPARA Anticorps) signaling, inhibiting the TLR4 (Montrer TLR4 Anticorps)-mediated NF-kappaB (Montrer NFKB1 Anticorps) signaling pathway, and interfering with the ERK1/2-dependent signaling cascade (TLR4 (Montrer TLR4 Anticorps)/ERK1/2/AP-1 (Montrer FOSB Anticorps)/STAT3 (Montrer STAT3 Anticorps)), which suggests that OEA may be a therapeutic agent for inflammatory diseases.

8. the physiological role of the negative crosstalk between the cAMP/PKA/AKAP4 and the PKC/ERK1/2 pathways is to regulate capacitation and acrosome reaction.

9. co-treatment with curcumin and cisplatin synergistically induces apoptosis through ROS-mediated activation of ERK1/2 in bladder cancer

10. ERK1/2 and p-ERK1/2 seem to be important in the development of Gallbladder cancer (GBC).

Mouse (Murine) Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

1. In a retinitis pigmentosa mouse model, TrkC (Montrer NTRK3 Anticorps) activity generates phosphorylated Erk (Montrer EPHB2 Anticorps), which upregulates glial TNF-alpha (Montrer TNF Anticorps), causing selective neuronal death.

2. A. fumigatus increased PAR-2 expression and elevated disease, PMN infiltration, and proinflammatory cytokine expreERK1 Kinasession through PAR-2, which may be modified by p-ERK1/2.

3. ERK1 and ERK2 (Montrer MAPK1 Anticorps) play specific roles in beta cells. ERK2 (Montrer MAPK1 Anticorps) cannot always compensate for the lack of ERK1 but the absence of a clear-cut phenotype in Erk1 (-/-) mice shows that ERK1 is dispensable in normal conditions.

4. The Macrophage Activation Induced by Bacillus thuringiensis Cry1Ac Protoxin Involves ERK1/2 and p38 (Montrer CRK Anticorps) Pathways and the Interaction with Cell-Surface-HSP70 (Montrer HSP70 Anticorps).

5. hBD-1 potentiates the induction of in vitro osteoclastogenesis by RANKL via enhanced phosphorylation of the p44/42 MAPKs.

6. ERK1 role in the osteoclast differentiation.Insulin induces RANK expression via ERK1/2, which contributes to the enhancement of osteoclast differentiation.

7. Suppressing P38 (Montrer CRK Anticorps) promoted adipogenic trans-differentiation and intensified adipolytic metabolism in differentiated cells. However, inhibition of ERK1/2 had the opposite effects on adipogenesis and no effect on adipolysis. Blocking JNK (Montrer MAPK8 Anticorps) weakly blocked trans-differentiation but stimulated adipolysis and induced apoptosis.

8. Taken together, the results of our present study indicated that DHCE could inhibit cellular proliferation and induce cell apoptosis in myeloma cells mediated through different mechanisms, possibly through inhibiting the IL-6/STAT3 and ERK1/2 pathways. And it may provide a new therapeutic option for MM patients.

9. Betacellulin (Montrer BTC Anticorps) promotes the proliferation of corneal epithelial stem cells through the phosphorylation of Erk1/Erk2 (Montrer MAPK1 Anticorps).

10. North American ginseng inhibits myocardial NOX2 (Montrer CYBB Anticorps)-ERK1/2-TNF-alpha (Montrer TNF Anticorps) signaling pathway and improves cardiac function in endotoxemia, suggesting that NA ginseng may have the potential in the prevention of clinical sepsis.

Zebrafish Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

1. MAPK3 role in the oocyte maturation

2. ERK1/2-Akt1 (Montrer AKT1 Anticorps) crosstalk regulates arteriogenesis in mice and zebrafish.

3. eena (Montrer SH3GL1 Anticorps) plays an important role in the development of the myeloid cell through activation of the ERK1/ERK2 (Montrer MAPK1 Anticorps) pathway

4. ERK1 and ERK2 (Montrer MAPK1 Anticorps) target common and distinct gene sets, confirming diverse roles for these kinases during embryogenesis; for ERK1 different specific genes involved in dorsal-ventral patterning and subsequent embryonic cell migration were identified.

5. These results demonstrate that induction of Hsp70 (Montrer HSPA1A Anticorps) in response to heat stress is dependent on ERK (Montrer MAPK1 Anticorps) activation in Pac2 (Montrer PSMG2 Anticorps) cells.

6. Data define distinct roles for ERK1 and ERK2 (Montrer MAPK1 Anticorps) in developmental cell migration processes during zebrafish embryogenesis.

Cow (Bovine) Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

1. MAPK3/1 is involved in luteinizing hormone-mediated decrease of C-type natriuretic peptide and this process is related to the EGFR (Montrer EGFR Anticorps) and MAPK3/1 signal pathways

2. Chronic hypoxia induces Egr-1 via activation of ERK1/2 and contributes to pulmonary vascular remodeling.

3. ER Ca(2+) release enhances eNOS Ser-635 phosphorylation and function via ERK1/2 activation.

4. Thrombospondin 1 (Montrer THBS1 Anticorps), fibronectin (Montrer FN1 Anticorps), and vitronectin (Montrer VTN Anticorps) are differentially dependent upon RAS, ERK1/2, and p38 (Montrer MAPK14 Anticorps) for induction of vascular smooth muscle cell chemotaxis.

5. results suggest that Nav1.7-Ca2+ influx-protein kinase C-alpha pathway activated ERK1/ERK2 and p38, which increased phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation

6. These data suggest that Gab1-ERK1/2 binding and their nuclear translocation play a crucial role in Egr-1 (Montrer EGR1 Anticorps) nuclear accumulation.

7. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt, mTOR, p70S6K, and ERK1/2.

8. This study demonstrates for the first time that cyclic mechanical stretch induces the proliferation of bovine satellite cells and suppresses their myogenic differentiation through the activation of ERK (Montrer MAPK1 Anticorps).

9. findings indicate that exposure to DHEA, at concentrations found in human blood, causes vascular endothelial proliferation by a plasma membrane-initiated activity that is Gi/o and ERK1/2 dependent.

10. Results suggest that estrogen receptors and the ERK1/2 signaling pathway are involved in the anti-apoptotic action of LY117018 in vascular endothelial cells.

Pig (Porcine) Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

1. Early activation of MAPK p44/42 is involved in deoxynivalenol -induced disruption of intestinal barrier function and tight junction network signaling.

2. Pseudorabies virus glycoprotein gE-mediated ERK 1/2 phosphorylation also occurs in epithelial cells and in these cells, gE-mediated ERK 1/2 signaling is associated with degradation of the pro-apoptotic protein Bim (Montrer BCL2L11 Anticorps).

3. Treatment with ERK inhibitors or ERK1/2 knockdown significantly suppressed porcine epidemic diarrhea virus progeny production.

4. This study reveals a new function of the gE glycoprotein of pseudorabies virus and suggests that pseudorabies virus, through activation of ERK1/2 signaling, has a substantial impact on T cell behavior.

5. CSF2 (Montrer CSF2 Anticorps) stimulates proliferation of trophectoderm cells by activation of the PI3K-and ERK1/2 MAPK (Montrer MAPK1 Anticorps)-dependent MTOR (Montrer FRAP1 Anticorps) signal transduction cascades.

6. PGRN (Montrer GRN Anticorps) inhibits adipogenesis in porcine preadipocytes partially through ERK (Montrer MAPK1 Anticorps) activation mediated PPARgamma (Montrer PPARG Anticorps) phosphorylation.

7. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK (Montrer PRKAA1 Anticorps)/ERK (Montrer MAPK1 Anticorps)/TSC2 (Montrer TSC2 Anticorps)/mTOR (Montrer FRAP1 Anticorps) signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

8. Data show that proinflammatory cytokines induction was ERK1/2 and JNK1 (Montrer MAPK8 Anticorps)/2 dependent.

9. Saccharomyces cerevisiae inhibits the Enterotoxigenic Escherichia coli-induced expression of pro-inflammatory transcripts and this inhibition was associated to a decrease of ERK1/2 and p38 MAPK (Montrer MAPK14 Anticorps) phosphorylation

10. ERK1 phosphorylation in response to Insulin-like Growth Factor-1 (Montrer IGF1 Anticorps) does not require activation of the Insulin-like Growth Factor-1 receptor tyrosine kinase (Montrer IGF1R Anticorps)

Candida albicans Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

1. The results suggest that the MPK-1 (Montrer MAPK1 Anticorps)/ERK (Montrer MAPK1 Anticorps) regulatory network, including FBF-1 (Montrer FBF1 Anticorps), FBF-2, and LIP-1 (Montrer CENPJ Anticorps), controls the number of sperm by regulating the timing of the sperm-oocyte switch in C. elegans.

2. Cek2 (Montrer FGFR3 Anticorps) has a cryptic role in cell-wall biogenesis and its role is not entirely redundant to Cek1.

3. knockdown of SUV420H1 (Montrer SUV420H1 Anticorps) reduced phosphorylated ERK1 and total ERK1 proteins, and interestingly suppressed ERK1 at the transcriptional level

4. Secreted aspartic protease-mediated proteolytic cleavage of Msb2 is required for activation of the Cek1 mitogen activated protein kinase (Montrer MAPK1 Anticorps) pathway in response to environmental cues.

5. The authors propose that a Msb2, Cek1 and Ace2 signalling pathway addresses PMT genes as downstream targets and that different modes of regulation have evolved for PMT1 and PMT2/PMT4 genes.

6. Msb2 is involved in the transmission of the signal toward Cek1 mediated by the Cdc42 (Montrer CDC42 Anticorps) GTPase (Montrer RACGAP1 Anticorps).

Arabidopsis thaliana Mitogen-Activated Protein Kinase 3 (MAPK3) interaction partners

1. abscisic acid and jasmonate mediate inactivation of the immune-associated MAP kinases (MAPKs), MPK3 and MPK6 (Montrer MAPK6 Anticorps), in Arabidopsis thaliana ABA induced expression of genes encoding the protein phosphatases 2C (PP2Cs), HAI1 (Montrer SPINT1 Anticorps), HAI2 (Montrer SPINT2 Anticorps), and HAI3 through ABF/AREB transcription factors

2. Constitutive active-MPK3 plants are more resistant to the hemibiotrophic pathogen Pseudomonas syringae DC3000.

3. constitutively active (CA)-MPK3 crosses with summ1 and summ2, two known suppressors of mpk4 (Montrer MAPK4 Anticorps), resulted in a partial reversion of the CA-MPK3 phenotypes.

4. that MPK3/MPK6 (Montrer MAPK6 Anticorps) phosphorylate and destabilize ICE1, which negatively regulates CBF (Montrer CEBPZ Anticorps) expression and freezing tolerance in plants

5. Changes in PUB22 Ubiquitination Modes Triggered by MITOGEN-ACTIVATED PROTEIN KINASE3 Dampen the Immune Response

6. MPK3 role in ultraviolet induced stomatal closure

7. Study propose that the pathogen-responsive MPK3/MPK6 (Montrer MAPK6 Anticorps) cascade and ABA are two essential signaling pathways that control, respectively, the organic acid metabolism and ion channels, two main branches of osmotic regulation in guard cells that function interdependently to control stomatal opening/closure.

8. Data report that MPK3/MPK6 and their substrate ERF6 promote the biosynthesis of IGSs and the conversion of I3G to 4MI3G, a target of PEN2/PEN3-dependent chemical defenses in plant immunity.

9. Data show that the protein kinases MPK3 and MPK6 (Montrer MAPK6 Anticorps) can both interact with SPOROCYTELESS/NOZZLE (SPL (Montrer SGPL1 Anticorps)) in vitro and in vivo and can phosphorylate the SPL (Montrer SGPL1 Anticorps) protein in vitro.

10. MKK4 (Montrer MAP2K4 Anticorps), MKK5 (Montrer MAP2K5 Anticorps), MKK7 (Montrer MAP2K7 Anticorps), and MKK9, are responsible for the activation of MPK3 and MPK6 (Montrer MAPK6 Anticorps) by melatonin, indicating that melatonin-mediated innate immunity is triggered by MAPK (Montrer MAPK1 Anticorps) signaling through MKK4 (Montrer MAP2K4 Anticorps)/5/7/9-MPK3/6 cascades.