Aperçu des produits pour anti-MAPKAP Kinase 5 (MAPKAPK5) Anticorps

Full name:: anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 Anticorps (MAPKAPK5)

Chez www.anticorps-enligne.fr sont 178 Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) Anticorps de 20 de différents fournisseurs disponibles. De plus, nous expédions MAPKAP Kinase 5 Protéines (12) et MAPKAP Kinase 5 Kits (3) et beaucoup plus de produits pour cette protéine. Un total de 210 MAPKAP Kinase 5 produits sont actuellement listés.

Synonymes:: MAPKAP-K5, MAPKAPK5, MK-5, MK5, PRAK

afficher tous les anticorps	Gène	GeneID	UniProt
	MAPKAPK5	17165	O54992
	MAPKAPK5	8550	Q8IW41
	MAPKAPK5	498183
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Human Monoclonal MAPKAP Kinase 5 Primary Antibody pour IHC, ELISA - ABIN969362 : Paliga, Natale, Watson: p38 mitogen-activated protein kinase (MAPK) first regulates filamentous actin at the 8-16-cell stage during preimplantation development. dans Biology of the cell / under the auspices of the European Cell Biology Organization 2005 (PubMed)
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Human Polyclonal MAPKAP Kinase 5 Primary Antibody pour IHC (p), WB - ABIN389587 : Daily, Monks, Leggas, Moscow: Abrogation of microcystin cytotoxicity by MAP kinase inhibitors and N-acetyl cysteine is confounded by OATPIB1 uptake activity inhibition. dans Toxicon : official journal of the International Society on Toxinology 2010 (PubMed)
Human Polyclonal MAPKAP Kinase 5 Primary Antibody pour ICC, IF - ABIN4347179 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. dans Nature methods 2013 (PubMed)

Plus d’anticorps contre MAPKAP Kinase 5 partenaires d’interaction

Mouse (Murine) Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) interaction partners

MK5 haplodeficiency attenuated the progression of hypertrophy, reduced collagen type 1 mRNA, and protected diastolic function in response to chronic pressure overload.
An alternative targeting strategy of MK5/PRAK (termed MK5/PRAK-Deltaex6) increased neither tumor incidence in the one step skin carcinogenesis model, nor Ras-induced transformation in primary cells.
MK5 positively regulates Rag transcription via phosphorylation of Foxo1 (Montrer FOXO1 Anticorps) in developing B cells.
observations have demonstrated that PRAK is not required for either the rottlerin-mediated anti-chlamydial activity or rottlerin inhibition of sphingolipid trafficking, suggesting rottlerin may achieve its inhibitory role by targeting other host factors
Results suggest that PRAK may function as a tumor suppressor in multiple types of cancers.
the regulation of neuronal morphogenesis is proposed as the first physiological function of the ERK3 (Montrer RYK Anticorps)/MK5 signaling module
It was shown that the tumor-suppressing and tumor-promoting functions of the p38 (Montrer CRK Anticorps)-PRAK pathway are temporally and spatially separated during cancer development in vivo, relying on the stimulus, and the tissue type and the stage of cancer development.
Rheb (Montrer RHEB Anticorps) inactivation by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1
MK5 co-immunoprecipitated ERK3 (Montrer RYK Anticorps), but not ERK4 (Montrer MAPK4 Anticorps) or p38 alpha (Montrer MAPK14 Anticorps), in control and hypertrophying hearts (MK5).
Both binding and activation of p38 mitogen-activated protein kinase (Montrer MAPK14 Anticorps) (MAPK (Montrer MAPK1 Anticorps)) play essential roles in regulation of the nucleocytoplasmic distribution of MAPK-activated protein kinase 5 by cellular stress.

Human Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) interaction partners

PRAK might be a potential therapeutic target of Alzheimer's disease involved in receptor for advanced glycation end products-mediated cell signaling induced by Abeta (Montrer APP Anticorps)
Plasma MAPKAPK5 protein was found to positively associate with the 10-year change in paired associates learning assessment in asymptomatic older twins.
Data highlight that DJ-1 (Montrer PARK7 Anticorps) is the downstream interacting target for PRAK, and in response to oxidative stress PRAK may exert a cytoprotective effect by facilitating DJ-1 (Montrer PARK7 Anticorps) to sequester Daxx (Montrer DAXX Anticorps) in the nucleus, thus preventing cell death.
Data indicate that the structurally most flexible regions during molecular dynamics (MD) simulations of the native mitogen-activated protein kinase (Montrer MAPK1 Anticorps)-activated protein kinase (Montrer CDK7 Anticorps) MK5 model were the loop regions.
Studies with specific phosphoantibodies indicate that MK5 phosphorylates Hsp40/DnaJB1 (Montrer DNAJB1 Anticorps) in vivo at Ser (Montrer SIGLEC1 Anticorps)-149 or/and Ser (Montrer SIGLEC1 Anticorps)-151 and Ser (Montrer SIGLEC1 Anticorps)-171 in the C-terminal domain of Hsp40/DnaJB1 (Montrer DNAJB1 Anticorps).
study shows Tip60 (Montrer KAT5 Anticorps) plays an essential role in oncogenic ras-induced senescence; revealed a cascade of posttranslational modifications involving p38 (Montrer CRK Anticorps), Tip60 (Montrer KAT5 Anticorps) and PRAK, 3 proteins essential for ras-induced senescence; these modifications are critical for prosenescent function of Tip60 (Montrer KAT5 Anticorps) and PRAK
these results firstly demonstrate that MK5 is degraded in response to doxorubicin and negatively regulates doxorubicin-induced apoptosis, providing novel insights into the molecular mechanism of doxorubicin resistance in hepatoma cells.
IGF2BP1 promotes the velocity and directionality of tumor-derived cell migration by determining the cytoplasmic fate of two novel target mRNAs: MAPK4 and PTEN
Rheb (Montrer RHEB Anticorps) inactivation by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1
Activation loop phosphorylation of ERK3/ERK4 (Montrer MAPK4 Anticorps) by group I p21 (Montrer CDKN1A Anticorps)-activated kinases (PAKs) defines a novel PAK-ERK3 (Montrer MAPK4 Anticorps)/4-MAPK-activated protein kinase 5 signaling pathway.

MAPKAP Kinase 5 (MAPKAPK5) profil antigène

Antigen Summary

The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.

Alternative names and synonyms associated with MAPKAP Kinase 5 (MAPKAPK5)

mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5) anticorps
mitogen-activated protein kinase-activated protein kinase 5 (mapkapk5) anticorps
MAP kinase-activated protein kinase 5 (Mapkapk5) anticorps
mitogen-activated protein kinase-activated protein kinase 5 (Mapkapk5) anticorps

MAPKAP-K5 anticorps
MAPKAPK5 anticorps
MK-5 anticorps
MK5 anticorps
PRAK anticorps

Protein level used designations for MAPKAPK5

mitogen-activated protein kinase-activated protein kinase 5 , MAP kinase-activated protein kinase 5 , MAP kinase-activated protein kinase 5-like , MAPK-activated protein kinase 5 , MAPKAP kinase 5 , MAPKAPK-5 , p38-regulated/activated protein kinase

GENE ID	SPECIES
100057579	Equus caballus
738233	Pan troglodytes
100017664	Monodelphis domestica
100230432	Taeniopygia guttata
100412389	Callithrix jacchus
100434701	Pongo abelii
100482977	Ailuropoda melanoleuca
100548508	Meleagris gallopavo
100553264	Anolis carolinensis
100582875	Nomascus leucogenys
17165	Mus musculus
8550	Homo sapiens
498183	Rattus norvegicus
373929	Gallus gallus
477480	Canis lupus familiaris
100153404	Sus scrofa
535625	Bos taurus

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Show all anti-Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) Anticorps with Pubmed References

Mouse (Murine) Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) interaction partners

Human Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5) interaction partners

Antigen Summary

Alternative names and synonyms associated with MAPKAP Kinase 5 (MAPKAPK5)

Protein level used designations for MAPKAPK5