anti-Souris Paxillin anticorps pour Western Blotting

Recommended Paxillin Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Paxillin (PXN) Anticorps
  • AW108311
  • AW123232
  • Pax
  • CG18061
  • CG18576
  • CG31794
  • CT40481
  • CT42454
  • DPaxillin
  • DPxn
  • DPxn37
  • Dmel\\CG31794
  • Dpax
  • DpaxA
  • PDLP
  • dPax
  • pax
  • wu:fw71f12
  • PXN
  • LOC100220858
  • paxillin
  • Paxillin
  • paxillin S homeolog
  • paxillin a
  • PXN
  • Pxn
  • Pax
  • pxn.S
  • pxna
  • LOC696336
  • pxn
Épitope
AA 456-472, C-Term
67
52
28
20
16
15
15
13
13
10
8
7
6
6
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
392
208
197
32
12
11
11
9
5
5
5
4
1
1
1
1
1
Hôte
Lapin
355
45
2
Clonalité
Polyclonal
Conjugué
Cet anticorp Paxillin est non-conjugé
7
7
7
5
5
5
5
5
5
5
5
5
4
4
2
2
2
2
2
Application
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
318
110
86
64
54
48
28
23
8
5
3
2
2
2
1
1
1
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N° du produit ABIN3044187
$ 280.00
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
3.2307212 ABIN3043666 ICC WB Mouse IgG1 AA 305-559, C-Term Connectez-vous pour afficher PXC-10 3
3.2307212 ABIN968067 IF IP IHC WB Mouse IgG1 AA 1-557 Connectez-vous pour afficher 165-Paxillin 5
3.2307212 ABIN2706774 IP IHC WB Rabbit Center Connectez-vous pour afficher Polyclonal 0
3.2307212 ABIN2706775 WB Rabbit pTyr118 Connectez-vous pour afficher Polyclonal 0
3.2307212 ABIN447010 ICC IF IHC (p) IHC WB Rabbit N-Term Connectez-vous pour afficher Polyclonal 1
3.2307212 ABIN968042 BI IP WB Mouse IgG1 AA 1-557 Connectez-vous pour afficher 177-Paxillin 5
3.2307212 ABIN968043 BI IP IHC WB Mouse IgG1 AA 1-557 Connectez-vous pour afficher 177-Paxillin 5
3.2307212 ABIN1531947 ELISA WB Rabbit IgG AA 15-64, pTyr31 Connectez-vous pour afficher Polyclonal 0
3.2307212 ABIN1531946 ELISA WB Rabbit IgG AA 85-134, pTyr118 Connectez-vous pour afficher Polyclonal 0
3.2307212 ABIN1532978 IHC ELISA WB Rabbit IgG AA 85-134 Connectez-vous pour afficher Polyclonal 0
3.2307212 ABIN967711 IHC (f) IF IP WB Mouse IgG1 AA 1-557 Connectez-vous pour afficher 349-Paxillin 5
3.2307212 ABIN967712 IHC (f) IF IP WB Mouse IgG1 AA 1-557 Connectez-vous pour afficher 349-Paxillin 5
3.2307212 ABIN1532979 IHC ELISA WB Rabbit IgG AA 15-64 Connectez-vous pour afficher Polyclonal 0
3.2307212 ABIN968066 IF IP IHC WB Mouse IgG1 AA 1-557 Connectez-vous pour afficher 165-Paxillin 4
3.2307212 ABIN408463 WB Rabbit IgG pTyr118 Connectez-vous pour afficher Polyclonal 0
3.2307212 ABIN1870552 WB Rabbit IgG pTyr31 Connectez-vous pour afficher Polyclonal 0
3.2307212 ABIN1870550 IHC WB Rabbit IgG pTyr118 Connectez-vous pour afficher Polyclonal 0
3.2307212 ABIN1874479 IHC IP WB Rabbit IgG Connectez-vous pour afficher Polyclonal 0
3.2307212 ABIN3186343 ELISA IF IHC WB Rabbit IgG Thr507 Connectez-vous pour afficher Polyclonal 0
3.2307212 ABIN3182119 ELISA IHC WB Rabbit IgG pTyr31 Connectez-vous pour afficher Polyclonal 0

General

Antigène Paxillin (PXN) Anticorps
Épitope AA 456-472, C-Term
(67), (52), (28), (20), (16), (15), (15), (13), (13), (10), (8), (7), (6), (6), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(392), (208), (197), (32), (12), (11), (11), (9), (5), (5), (5), (4), (1), (1), (1), (1), (1)
Hôte Lapin
(355), (45), (2)
Clonalité
Polyclonal
Conjugué Cet anticorp Paxillin est non-conjugé
(7), (7), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (2), (2), (2), (2), (2)
Application Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(318), (110), (86), (64), (54), (48), (28), (23), (8), (5), (3), (2), (2), (2), (1), (1), (1)
Pubmed 3 références disponible
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Détail du produit anti-Paxillin anticorps

Détail du antigène Paxillin Information d'application Stockage References for anti-Paxillin antibody (ABIN3044187) Images
Fonction Rabbit IgG polyclonal antibody for Paxillin(PXN) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Séquence HEKDGKAYCR KDYFDMF
Réactivité croisée (Details) No cross reactivity with other proteins.
Attributs du produit Rabbit IgG polyclonal antibody for Paxillin(PXN) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
Gene Name: paxillin
Protein Name: Paxillin
Purification Immunogen affinity purified.
Immunogène A synthetic peptide corresponding to a sequence at the C-terminal of human Paxillin(456-472aa HEKDGKAYCRKDYFDMF), identical to the related mouse and rat sequences.
Isotype IgG

Détail du antigène Paxillin

Détail du produit anti-Paxillin anticorps Information d'application Stockage References for anti-Paxillin antibody (ABIN3044187) Images Haut de la page
Antigène
Autre désignation PXN (PXN Antibody Extrait)
Sujet PXN(Paxillin) is a signal transduction adaptor protein discovered in 1990 in the laboratory of Keith Burridge. Salgia et al.(1995) mapped the paxillin gene to 12q24 using fluorescence in situ hybridization.The C-terminal region of paxillin contains four LIM domains that target paxillin to focal adhesions, it is presumed through a direct association with the cytoplasmic tail of beta-integrin. The N-terminal region of paxillin is rich in protein-protein interaction sites. The proteins that bind to paxillin are diverse and include protein tyrosine kinases, such as Src and FAK, structural proteins, such as vinculin and actopaxin, and regulators of actin organization, such as COOL/PIX and PKL/GIT. Paxillin is tyrosine-phosphorylated by FAK and Src upon integrin engagement or growth factor stimulation, creating binding sites for the adapter protein Crk.The paxillin protein contains 4 LIM domains, a proline-rich domain containing a consensus SH3-binding site, and 3 potential SH2-binding sites. On Northern blots, paxillin was expressed as a 3.7-kb mRNA in all tissues tested.

Synonyms: FLJ16691 antibody|FLJ23042 antibody|Paired box protein Pax 1 antibody|PAX 1 antibody|PAX1 antibody|PAXI_HUMAN antibody|Paxillin alpha antibody|Paxillin antibody|PXN antibody|PXN protein antibody
UniProt P49023
Pathways Signalisation MAPK, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling

Information d'application

Détail du produit anti-Paxillin anticorps Détail du antigène Paxillin Stockage References for anti-Paxillin antibody (ABIN3044187) Images Haut de la page
Indications d'application WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Commentaires

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Restrictions For Research Use only

Stockage

Détail du produit anti-Paxillin anticorps Détail du antigène Paxillin Information d'application References for anti-Paxillin antibody (ABIN3044187) Images Haut de la page
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Agent conservateur Thimerosal (Merthiolate), Sodium azide
Précaution d'utilisation This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Date de péremption 12 months

References for anti-Paxillin antibody (ABIN3044187)

Détail du produit anti-Paxillin anticorps Détail du antigène Paxillin Information d'application Stockage Images Haut de la page
Produit citée dans:

Zhu, Liu, Li, Liu, Wang, Sun, Xiong, Jiang, Zheng, Hu: "Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility." dans: Carcinogenesis, Vol. 35, Issue 8, pp. 1901-10, 2014

Liu, Zhu, Xiong, Zheng, Hu, Qiu: "Knockdown of protein tyrosine phosphatase receptor U inhibits growth and motility of gastric cancer cells." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 9, pp. 5750-61, 2014

Zhong, Luo, Wang, Tang, Wu, Wang, Huang, Sun, Huang: "Effects of polydopamine functionalized titanium dioxide nanotubes on endothelial cell and smooth muscle cell." dans: Colloids and surfaces. B, Biointerfaces, Vol. 116, pp. 553-60, 2014

Images

Détail du produit anti-Paxillin anticorps Détail du antigène Paxillin Information d'application Stockage References for anti-Paxillin antibody (ABIN3044187) Haut de la page
Images (Fournisseur)
Western Blotting (WB) image for anti-Paxillin (PXN) (AA 456-472), (C-Term) antibody (ABIN3044187) Anti-Paxillin antibody, Western blotting Lane 1: 293T Cell Lysate Lane 2: HELA Cell L...
Immunohistochemistry (IHC) image for anti-Paxillin (PXN) (AA 456-472), (C-Term) antibody (ABIN3044187) Anti-Paxillin antibody, IHC(F) IHC(F): Rat Kidney Tissue
Immunohistochemistry (IHC) image for anti-Paxillin (PXN) (AA 456-472), (C-Term) antibody (ABIN3044187) Anti-Paxillin antibody, IHC(P) IHC(P): Human Lung Cancer Tissue
Immunohistochemistry (IHC) image for anti-Paxillin (PXN) (AA 456-472), (C-Term) antibody (ABIN3044187) Anti-Paxillin antibody, ICC ICC: HELA Cell