Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher toutes les espèces
Afficher tous les synonymes
Sélectionnez vos espèces et l'application
anti-Mouse (Murine) IL1B Anticorps:
anti-Rat (Rattus) IL1B Anticorps:
anti-Human IL1B Anticorps:
Vous arrivez à notre recherche pré-filtrée.
Bacteria Polyclonal IL1B Primary Antibody pour ELISA, EM - ABIN269770
Petrovski, Ayna, Majai, Hodrea, Benko, Mádi, Fésüs: Phagocytosis of cells dying through autophagy induces inflammasome activation and IL-1β release in human macrophages. dans Autophagy 2011
Show all 23 Pubmed References
Dog (Canine) Polyclonal IL1B Primary Antibody pour IF (p), IHC (p) - ABIN728503
Zhong, Shu, Wang, Luo, Zhong, Ran, Zheng, Yin, Ling: Enhanced homing of mesenchymal stem cells to the ischemic myocardium by ultrasound-targeted microbubble destruction. dans Ultrasonics 2011
Show all 15 Pubmed References
Human Monoclonal IL1B Primary Antibody pour CyTOF, FACS - ABIN4899223
Yates, Burgess, Kocsis-Angle, Antal, Dority, Embury, Piotrkowski, Brunden: Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. dans Journal of neurochemistry 2000
Show all 15 Pubmed References
Human Polyclonal IL1B Primary Antibody pour ELISA, ICC - ABIN6262623
Ding, Xu, Wang, Zhang: Rotenone Attenuates Renal Injury in Aldosterone-Infused Rats by Inhibiting Oxidative Stress, Mitochondrial Dysfunction, and Inflammasome Activation. dans Medical science monitor : international medical journal of experimental and clinical research 2016
Show all 9 Pubmed References
Human Polyclonal IL1B Primary Antibody pour IHC (p), IHC - ABIN446969
Omran, Peng, Zhang, Xiang, Xue, Gan, Kong, Yin: Interleukin-1β and microRNA-146a in an immature rat model and children with mesial temporal lobe epilepsy. dans Epilepsia 2012
Show all 9 Pubmed References
Human Polyclonal IL1B Primary Antibody pour IHC, WB - ABIN6672481
Wu, Zhang, Qi, Zhang, Li, Li, Lin, Bai, Liu, Chen, Yang, Xu, Zhang, Yang: Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis. dans Cell death & disease 2018
Show all 7 Pubmed References
Mouse (Murine) Polyclonal IL1B Primary Antibody pour IHC, WB - ABIN3021462
Du, Qiao, Chen, Chen, Liu, Lin, Wang, Xie: Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes. dans Frontiers in molecular neuroscience 2017
Show all 7 Pubmed References
Mouse (Murine) Polyclonal IL1B Primary Antibody pour Neut, WB - ABIN223538
Scott, Ma, Viriyakosol, Terkeltaub, Liu-Bryan: Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals. dans Journal of immunology (Baltimore, Md. : 1950) 2006
Show all 6 Pubmed References
Human Polyclonal IL1B Primary Antibody pour WB - ABIN5518922
Yao, Peng, Peng, Tan, Wu, Wu, Chen, Li, Li, Zhu: Effects of extract of Buddleja officinalis on partial inflammation of lacrimal gland in castrated rabbits with dry eye. dans International journal of ophthalmology 2012
Show all 5 Pubmed References
Mouse (Murine) Polyclonal IL1B Primary Antibody pour WB - ABIN5519006
Yu, Chen, Wang, Kuang, Liu, Zhang, Du: Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-?B and STAT3 in transient focal stroke. dans PLoS ONE 2013
Show all 5 Pubmed References
Macrophage-less irf8 mutants show prolonged inflammation with elevated levels of Tnf-alpha and Il-1beta.
This study reveals that proper levels of Il1b signaling and tissue inflammation, which are tuned by macrophages, play a crucial role in tissue regeneration.
Leukocyte expression of IL-1beta was detectable only following injury, which activated leukocytes throughout zebrafish embryos in a caspase dependent manner.
Embryo and larva leukocytes upregulate IL-1beta expression proportional to the dose of ultraviolet radiation exposure in an immune response at the organismal level.
findings reveal that the Il-1beta-Myd88 axis and NADPH oxidase-mediated ROS signaling are two independent pathways that differentially regulate neutrophil migration during sterile inflammation.
the expression levels of IL-1beta and TNF-alpha in high cholesterol diet (HCD)-fed zebrafish larvae
These results represent the first demonstration of processing and secretion of zebrafish IL-1beta in response to a pathogen.
Study in transgenic mice found that barrier breakdown and expression of inflammatory factors contribute to development of serrated polyps. Subsets of cecal PDGFRA+ fibroblasts are activated by release of Il1b from myeloid cells during the early stages of serrated polyp development. Mmp3 produced by PDGFRA+ fibroblasts is important for serrated polyp development.
These results establish the ripoptosome/caspase-8 complex as a pro-inflammatory checkpoint that senses the perturbation of mitochondrial integrity.
the pathway regulating the trafficking of IL-1alpha is distinct from the pathway regulating IL-1beta and IL-18. Although the release of IL-1alpha could also be dissociated from cell death, it was independent of the effects of the membrane-stabilizing agent punicalagin, which inhibited both IL-1beta and IL-18 release.
In vitro and in vivo data showed that IL-1beta induces Th17 polarization and increases GMCSF production by T cells. In the T-cell transfer colitis model, Nlrp3 deficiency resulted in lower IL1beta levels, reduced Th17 immunity, and less severe colitis. This study demonstrates that Nlrp3 acts as a molecular switch of intestinal homeostasis by shifting local immune cells toward an inflammatory phenotype via IL-1beta.
L. amazonensis elimination mediated by P2X7 receptor and LTB4 was dependent on non-canonical NLRP3 inflammasome activation, ROS production, and IL-1beta signaling.
Enhanced IL-1beta production is mediated by a TLR2-MYD88-NLRP3 signaling axis during coinfection with influenza A virus and Streptococcus pneumoniae.
PERK inhibition, on the other hand, controls caspase-1-mediated conversion of proIL-1beta to mIL-1beta. These findings reveal translation-independent functions of PERK and IRE1alpha: PERK controls the production of mIL-1beta, which is then followed by GRASP55 and IRE1alpha activity to keep mIL-1beta in a secretion-competent form.
IL1beta and TNFalpha enhance RANKL-dependent expression of adseverin, which contributes to fusion processes in osteoclastogenesis
JunD blunts ischemia/reperfusion-induced brain injury via suppression of IL-1beta.
The results suggest that certain species of commensal bacteria in post-weaning mice aggravate ovalbumin-induced allergic asthma through NLRP3/IL1B signal pathway.
Ferrylhemoglobin is a potent trigger of NLRP3 activation and production of IL-1beta in vitro and in vivo.
mitochondrial IL-1beta production by bone marrow-derived macrophages was significantly reduced in ATF3 KO mice as a result of the disruption of cellular ROS and Ca(2+) homeostasis. Accordingly, ATF3 KO mice displayed diminished survival and bacterial clearance following S. pneumoniae infection.
Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1beta. Neutrophil extravasation was mediated by MyD88-dependent IL-1beta production by graft-infiltrating classical monocytes, which downregulated the expression of the tight junction-associated protein ZO-2 in pulmonary vascular endothelial cells.
These findings reveal a novel mechanism of acute hyperglycemia postburn in which impaired insulin secretory capacity mediated by IL-1beta leads to acute hyperglycemia.
Investigation of 2-AP demonstrated its nociception inhibition and ability to reduce reactive oxygen species. Its interaction with A2a receptors may well be related to proinflammatory cytokines TNF-alpha and IL-1beta reduction activity, corroborating its antinociceptive effect.
The data of this study presented here indicates that TGFbeta1 plays a role in the pathogenesis of hepatic encephalpoathy by inducing microglia activation and neuroinflammation.
These results suggest that an IL-1beta activation pathway, different from NLRP3 inflammasomes, plays an important role in pressure overload-induced sustained atrial fibrillation.
these findings reveal unexpected regulation of IL-1beta production by neutrophils in response to pathogenic fungi
IL-1 alpha/beta plays a positive role in muscle regeneration by coordinating the initial interactions among inflammatory microenvironments and satellite cells.
Pre-pregnancy exposure to diesel exhaust predisposes offspring to asthma through IL-1beta and IL-17A.
Findings suggested that IL-6 concentrations are elevated in stable patients with schizophrenia. Whereas IL-2 specifically marks severity of the motivation and pleasure domain of negative symptoms, IL-1beta is not specific to this dimension as it also predicts severity of general and global symptomatology.
In its role as a highly expressed mediator of sterile inflammation in Kawasaki disease, S100A12 appears to activate human coronary artery endothelial cells in an IL-1beta-dependent manner. These data provide new mechanistic insights into the contributions of S100A12 and IL-1beta to disease pathogenesis.
polymorphisms within IL1B and IL6 alter the expression of structural and fibril-associated extracellular matrix components and possibly modulate the susceptibility to anterior cruciate ligament injuries
Intracellular cytokine staining demonstrated monocytes are the major producers of IL-1beta in human whole blood cultures, and this was associated with activation of caspase-1/4/5, as detected by a fluorescently labelled caspase-1/4/5 probe.
After adjustment by Bonferroni correction, only the IL1B rs16944 and IL6 rs1800796 polymorphisms were significantly associated with risk of recurrent pregnancy loss.
We found increased IL-23 and IL-1beta expression in the Hashimoto thyroiditis group but not in the Graves disease group
An MALAT1/miR-145 axis contributes to ECM degradation in IL-1beta-induced chondrocytes through targeting ADAMTS5.
polymorphism in the IL1B gene is associated with diabetic nephropathy in type 2 diabetes patients in Poland
IL-1beta-induced autophagy is not disadvantageous for the survival of modern Mycobacterium tuberculosis strains, which reside within Rab5-positive phagosomal vesicles and avoid autophagosome engulfment.
Genetic polymorphisms in IL1B predict susceptibility to steroid-induced osteonecrosis of the femoral head in Chinese Han population.
These results suggest that repetitive transcranial magnetic stimulation may increase BDNF and decrease IL-1beta and TNF-alpha serum levels in elderly patients with refractory depression.
IL-1beta can delay vascular dementia occurrence and development through the P38-MAPK signaling pathway to regulate cell apoptosis and improve learning ability.
These findings suggest that the C3953T polymorphism could be considered as a potential biomarker for a genetic diagnosis of male infertility.
IL1beta and TNFalpha established a feedback loop to upregulate ARG2 expression via p38 and extracellular regulated kinases 1/2 (ERK1/2) signaling in neuroblastoma and neural crest-derived cells.
MiR-19b-3p attenuates IL-1beta induced extracellular matrix degradation and inflammatory injury in chondrocytes by targeting GRK6.
Gene polymorphism of IL-1beta (-511) can be used as a marker of progression of glomerulonephritis, nephrotic syndrome but more studies are needed.
Polymorphism of the IL-1beta, TNF, IL-1RA and IL-4 Cytokine Genes Significantly Increases the Risk of Preterm Birth
the IL-1beta-IL-1R signaling pathway may contribute to skin inflammation and psoriasis pathogenesis via the direct regulation of dermal IL-17-producing cells and stimulation of keratinocytes for amplifying inflammatory cascade.
This study identifies a new function for IL-1beta in the onset or enhancement of cell-intrinsic immunity, with important implications for cGAS-STING in integrating inflammatory and microbial cues for host defense
These studies showed that classical swine fever virus-induced IL-1beta secretion was mediated by NLRP3 and that classical swine fever virus infection could sufficiently activate the assembly of the NLRP3 inflammasome in monocytes.
Hsp90/Sec22b promotes the unconventional secretion of IL-1beta through an autophagosomal carrier during Mycoplasma hyopneumoniae infection.
Data indicated that Porcine reproductive and respiratory syndrome virus infection could induce IL-1beta up-regulation, which was likely mediated by MyD88/ERK/AP-1 and NLRP3 inflammasome.
Analysis of host-protein interactions for African swine fever virus L83L identified IL-1beta as its host ligand. A recombinant African swine fever virus lacking the L83L was developed from the highly virulent field isolate Georgia2007 and was used to show that L83L is a non-essential gene.
This study showed that the presence of embryos in oviducts on days 2-3 after mating may influence the oviductal expression of the members of the IL-1beta system, determining the action of IL-1beta, which may be considered to be the earliest sign of pregnancy in pigs.
This study showed that classical swine fever virus and p7 protein induced IL-1beta secretion and that p7 protein was a short-lived protein degraded by the proteasome.
local expression of IL-1beta and IL-8 in non-bacterial thrombotic endocarditis, Staphylococcus aureus infective endocarditis, animals with S. aureus sepsis without endocarditis and controls
IL1B regulates expression of IL1R1 and IL1RAP and stimulates expression of PTGS1 and PTGS2 that are considered to be the most rate-limiting enzymes for endometrial synthesis of prostaglandins during the peri-implantation period of pregnancy in pigs.
the results presented here strongly suggest IL-1beta as a key molecule guiding tissue remodelling events after myocardial infarction.
Mycobacterium bovis infected animals have a higher frequency of IFN-gamma producing CD4(+) T cells and elevated plasma IL-1beta levels.
The presence of embryos increased endometrial IL1B protein locally, while no differences regarding IL1R1 protein and IL1B and IL1R1 mRNA were detected.
For the inflammasome-dependent IL-1beta release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor.
Role of TGF-beta1 and TNF-alpha in IL-1beta mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.
Testicular IL-1 alpha and IL-1 beta concentrations were highest in the early post-natal period; however, IL-1 bioactivity and IL-6 concentrations were greatest in the immediate pre-pubertal period.
Data describe the expression of IL-8, IL-1beta and their respective receptors, CXCR1 and IL-1R1 in bovine theca cells, and suggest that VEGF is associated with the IL system in theca cells in ovary.
Genes for IL-1alpha and IL-1beta are expressed and a functional IL-1R is present in bovine corpora lutea throughout luteal phase. IL-1alpha and IL-1beta may have different roles as regulating PGF(2alpha) and PGE(2) production during luteal phase.
non-metalloproteinase mechanisms participate in IL-1-induced matrix degradation and loss of tissue material properties
Lipopolysaccharide stimulation up-regulates the secretion of cytokines by bovine polymorphonuclear neutrophil leukocytes.
dynamic compression stimulates cell proliferation and proteoglycan synthesis in the presence of IL-1beta and/or inhibitors of the MAPKs and NFkappaB and AP-1 signalling pathways
These results indicate that activation of the intrinsic antistaphylococcal response in bovine endothelial cells (BEC), enhanced by TNF-alpha and IL-1beta, is effective to eliminate S. aureus and S. epidermidis.
the low friction of articular cartilage can be modified by TGF-beta1 and IL-1beta treatment and that the friction coefficient depends on multiple factors, including superficial zone protein localization and surface roughness
These results suggest that IL-1alpha and IL-1beta are produced by the stromal cells, that IL-1beta is produced by the epithelial cells, and that IL-1alpha is a more potent stimulator of prostaglandin and plasminogen activator in bovine endometrial cells.
Data suggest an important regulatory mechanism of interleukin-1beta production, associated with microglial migration and proliferation, driven by ECM degradation and/or synthesis in an injured brain.
Mild heat shock increased the production of inflammatory cytokines, IL-1beta and IL-6 in rabbit cornea cells.
IL-1beta and TNF-alpha expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta and TNF-alpha.
IL-1beta induced a significant reduction in the relative intrinsic activity of GLUT5 and in this decrease are involved NO signal pathways; blockage of D-fructose intestinal uptake by IL-1beta may play an essential role in the pathophysiology of septic shock.
The inhibitory effect of IL-1beta on D-galactose absorption across mucosal side of enterocyte could be mediated by the activation of several kinases and nuclear factor kappa B.
Glucosamine hydrochloride treatment can can partially decrease the expression levels of IL-1 beta and increase the expression levels of TGF-beta 1, which delays the development of osteoarthritis.
In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of IL1B transcripts depending on luteal stage.
results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta,COX-2, and TGFbeta1
Increased PGE2 production led to reduction in 5-LO products in LPS-treated equine whole blood via IL-1b.
Results suggested that chemokine expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.
IL-1beta-induced up-regulation of matrix metalloproteinase 13 mRNA was blocked by all concentrations of geldanamycin tested
This study examined effects of in vitro exposure to solutions of hay dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
The effects of semen extender and seminal plasma on the expression of inflammatory modulators in the endometrium of mares are reported.
The acute pulmonary neutrophilia characteristic of recurrent airway obstruction was not associated with an increase in expression of chemokines in pulmonary mononuclear cells from disease-susceptible horses.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
, IL-1 beta
, interleukin-1 beta
, preinterleukin 1 beta
, prointerleukin-1 beta
, Interleukin-1 beta
, precursor interleukin-1beta
, interleukin-1 beta proprotein
, interleukin 1 beta
, lymphocyte proliferation-potentiating factor