anti-Humain IL1R1 anticorps pour Immunoprecipitation

Recommended IL1R1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Interleukin 1 Receptor, Type I (IL1R1) Anticorps
  • CD121A
  • D2S1473
  • IL-1R-alpha
  • IL1R
  • IL1RA
  • P80
  • CD121a
  • CD121b
  • IL-iR
  • Il1r-1
  • interleukin 1 receptor type 1
  • interleukin 1 receptor, type I
  • IL1R1
  • Il1r1
Épitope
AA 1-332
23
22
15
15
10
9
8
7
7
6
6
6
6
6
5
5
5
3
2
2
2
1
1
1
1
1
1
1
1
1
Reactivité
Humain
161
114
60
2
2
2
1
1
1
1
1
1
Hôte
Lapin
159
38
32
15
7
1
Clonalité
Polyclonal
Conjugué
Cet anticorp IL1R1 est non-conjugé
18
13
10
10
8
5
4
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
Application
ELISA, Immunoprecipitation (IP), Western Blotting (WB)
147
94
69
46
36
26
18
15
12
9
5
5
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
Fournisseur
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N° du produit (Fournisseur)
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N° du produit ABIN1995763
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN116871 EIA IP Rabbit Connectez-vous pour afficher Polyclonal 10
1 ABIN2935315 IF/ICC IHC IP WB Rabbit AA 120-208 Connectez-vous pour afficher Polyclonal 0
1 ABIN2935313 IF/ICC IHC IP WB Rabbit AA 21-109 Connectez-vous pour afficher Polyclonal 0
1 ABIN799832 IP RIA ELISA Rabbit Extracellular Domain Connectez-vous pour afficher Polyclonal 0
1 ABIN2935314 IF/ICC IHC IP WB Rabbit AA 226-318 Connectez-vous pour afficher Polyclonal 0
1 ABIN6024272 IF/ICC IHC IP WB Mouse Connectez-vous pour afficher 0

General

Antigène Interleukin 1 Receptor, Type I (IL1R1) Anticorps
Épitope AA 1-332
(23), (22), (15), (15), (10), (9), (8), (7), (7), (6), (6), (6), (6), (6), (5), (5), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain
(161), (114), (60), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Hôte Lapin
(159), (38), (32), (15), (7), (1)
Clonalité
Polyclonal
Conjugué Cet anticorp IL1R1 est non-conjugé
(18), (13), (10), (10), (8), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application ELISA, Immunoprecipitation (IP), Western Blotting (WB)
(147), (94), (69), (46), (36), (26), (18), (15), (12), (9), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 référence disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-IL1R1 anticorps

Détail du antigène IL1R1 Information d'application Stockage References for anti-IL1R1 antibody (ABIN1995763) Images
Specificité Human IL1R1 / CD121a
Attributs du produit Produced in rabbits immunized with purified, recombinant Human IL1R1 (rh IL1R1, ABIN2002132 NP_000868.1, Met 1-Thr 332,. IL1R1 specific IgG was purified by human IL1R1 affinity chromatography.
Purification purified by affinity chromatography
Stérilité 0.2 μm filtered
Immunogène Recombinant Human IL1R1 protein (ABIN2002132)
Isotype IgG
Plasmids, Primers & others

Détail du antigène IL1R1

Détail du produit anti-IL1R1 anticorps Information d'application Stockage References for anti-IL1R1 antibody (ABIN1995763) Images Haut de la page
Antigène
Autre désignation IL1R1 (IL1R1 Antibody Extrait)
Sujet Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA). IL-1R1/CD121a is an important mediator involved in many cytokine induced immune and inflammatory responses. This protein has been characterized by pharmacological and molecular techniques in the mouse brain. The spindle-shaped astrocytes enclose the wound, separating the healthy from damaged neural tissue. The shape change and subsequent repair processes are IL-1β activity-dependent, acting through the IL-1 type 1 receptor (IL-1R1), as co-application of the IL-1type 1 receptor antagonist protein (IL-1ra) blocks IL-1β induced effects. In the spleen, a slight increase in IL-1R AcP and IL-1R1 was observed during the first hours following LPS stimulation. In conclusion, IL-1R AcP mRNA is expressed in the brain and in other tissues where IL-1R1/CD121a transcripts are found. However, the regulation of its expression is distinct from IL-1R1/CD121a. The high level of expression and the lack of regulation of IL-1R AcP transcripts in the brain under inflammatory conditions suggest that the protein might be constitutively expressed in excess.
NCBI Accession NP_000868.1
Pathways Signalisation NF-kappaB, Carbohydrate Homeostasis

Information d'application

Détail du produit anti-IL1R1 anticorps Détail du antigène IL1R1 Stockage References for anti-IL1R1 antibody (ABIN1995763) Images Haut de la page
Indications d'application WB: 5-10 μg/mL
ELISA: 0.5-1.0 μg/mL
This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human IL1R1. The detection limit for Human IL1R1 is 0.00245 ng/well.
IP: 1-4 μg/mg of lysate
Restrictions For Research Use only

Stockage

Détail du produit anti-IL1R1 anticorps Détail du antigène IL1R1 Information d'application References for anti-IL1R1 antibody (ABIN1995763) Images Haut de la page
Format Liquid
Buffer 0.2 μm filtered solution in PBS
Agent conservateur Without preservative
Conseil sur la manipulation Avoid repeated freeze-thaw cycles.
Stock 4 °C,-20 °C,-80 °C
Stockage commentaire This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Date de péremption 12 months

References for anti-IL1R1 antibody (ABIN1995763)

Détail du produit anti-IL1R1 anticorps Détail du antigène IL1R1 Information d'application Stockage Images Haut de la page
Background publications

Vigers, Anderson, Caffes, Brandhuber: "Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta." dans: Nature, Vol. 386, Issue 6621, pp. 190-4, 1997

Images

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Images (Fournisseur)
Western Blotting (WB) image for anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 1-332) antibody (ABIN1995763) anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 1-332) antibody
Immunoprecipitation (IP) image for anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 1-332) antibody (ABIN1995763) anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 1-332) antibody (Image 2)