anti-Chien Insulin anticorps pour Immunohistochemistry (Frozen Sections)

Recommended Insulin Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Insulin (INS) Anticorps
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • INS-IGF2
  • Ins2
Reactivité
Chat, Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Porc, Lapin, Rat (Rattus), Mouton
877
388
275
264
208
125
49
8
6
5
5
4
3
2
2
1
1
1
1
1
1
1
Hôte
Souris
709
192
50
16
3
1
Clonalité
Monoclonal
Conjugué
Cet anticorp Insulin est non-conjugé
48
38
38
23
22
22
22
17
17
14
14
14
14
14
14
14
14
10
9
8
8
8
5
5
5
5
5
5
2
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
504
370
251
239
189
181
146
123
73
66
32
26
24
15
7
6
5
4
4
3
2
1
1
1
1
1
1
1
Fournisseur
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N° du produit ABIN114751
$ 308.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN114750 IHC (fro) IHC (p) Mouse IgG1 Connectez-vous pour afficher K36aC10 0

General

Antigène Insulin (INS) Anticorps
Reactivité Chat, Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Porc, Lapin, Rat (Rattus), Mouton
(877), (388), (275), (264), (208), (125), (49), (8), (6), (5), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Hôte Souris
(709), (192), (50), (16), (3), (1)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp Insulin est non-conjugé
(48), (38), (38), (23), (22), (22), (22), (17), (17), (14), (14), (14), (14), (14), (14), (14), (14), (10), (9), (8), (8), (8), (5), (5), (5), (5), (5), (5), (2), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(504), (370), (251), (239), (189), (181), (146), (123), (73), (66), (32), (26), (24), (15), (7), (6), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-Insulin anticorps

Détail du antigène Insulin Information d'application Stockage References for anti-Insulin antibody (ABIN114751) Images
Specificité This antibody recognizes purified Insulin from the pancreas of Human, Bovine, Horse, Sheep as well as Proinsulin from Human. Cross reaction has been observed with insulin containing cells in fixed sections of pancreas from Human, Porcine, Dog, Rabbit, Bovine, Sheep, Rat, Guinea Pig and Cat.
Cellular Localization: Cytoplasmic.Cellular Localization
Purification Supernatant
Immunogène Human insulin.
Clone K36aC10
Isotype IgG1

Détail du antigène Insulin

Détail du produit anti-Insulin anticorps Information d'application Stockage References for anti-Insulin antibody (ABIN114751) Images Haut de la page
Antigène
Autre désignation Insulin (INS Antibody Extrait)
Sujet Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS
ID gène 3630
NCBI Accession NP_000198
UniProt P01308
Pathways Signalisation NF-kappaB, Signalisation RTK, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

Information d'application

Détail du produit anti-Insulin anticorps Détail du antigène Insulin Stockage References for anti-Insulin antibody (ABIN114751) Images Haut de la page
Indications d'application Immunohistochemistry on Formalin/Paraffin Sections: Use a dilution of 1/25-1/50 in anABC method (30 minutes at room temperature). Recommended Positive Control: Pancreas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-Insulin anticorps Détail du antigène Insulin Information d'application References for anti-Insulin antibody (ABIN114751) Images Haut de la page
Format Liquid
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Insulin antibody (ABIN114751)

Détail du produit anti-Insulin anticorps Détail du antigène Insulin Information d'application Stockage Images Haut de la page
Background publications

Madsen: "Proinsulin-specific monoclonal antibodies. Immunocytochemical application as beta-cell markers and as probes for conversion." dans: Diabetes, Vol. 36, Issue 10, pp. 1203-11, 1987

Keilacker, Dietz, Witt, Woltanski, Berling, Ziegler: "Kinetic properties of monoclonal insulin antibodies." dans: Biomedica biochimica acta, Vol. 45, Issue 8, pp. 1093-102, 1986