anti-Souris RIPK1 anticorps pour ELISA

Recommended RIPK1 Antibody

Antigène
Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) Anticorps
  • RIP
  • RIP1
  • D330015H01Rik
  • Rinp
  • Rip1
  • rip1
  • ripk1
  • xRIP1beta
  • xrip1
  • receptor interacting serine/threonine kinase 1
  • receptor (TNFRSF)-interacting serine-threonine kinase 1
  • receptor interacting serine/threonine kinase 1 L homeolog
  • RIPK1
  • Ripk1
  • ripk1.L
Épitope
pSer161
18
13
8
8
7
7
7
4
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
Reactivité
Humain, Souris
165
57
47
8
4
3
3
1
1
Hôte
Lapin
137
31
3
Clonalité
Polyclonal
Conjugué
Cet anticorp RIPK1 est non-conjugé
10
6
6
6
5
5
5
5
5
3
2
2
2
1
1
1
1
Application
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
113
55
54
27
24
16
5
4
4
2
2
2
1
Options

Images

N° du produit ABIN6270166
$ 450.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
7.7934265 ABIN4350584 ELISA ICC IF IHC IHC (p) WB Rabbit N-Term Polyclonal 6
7 ABIN6269593 ELISA IHC WB Rabbit IgG pTyr384 Polyclonal 0
7 ABIN604700 ELISA IHC IHC (p) WB Rabbit IgG N-Term Polyclonal 0
7 ABIN1031543 IHC ELISA WB Rabbit N-Term Polyclonal 0
4 ABIN6271014 ELISA WB Rabbit IgG Polyclonal 0
4 ABIN6264764 ELISA WB Rabbit IgG Polyclonal 0
4 ABIN6270440 ELISA WB Rabbit IgG Polyclonal 0
4 ABIN1738881 IHC (p) ELISA WB Rabbit IgG N-Term Polyclonal 0
1 ABIN2861311 IF IHC ELISA WB Rabbit N-Term Polyclonal 0
1 ABIN6056277 ELISA Biotin Rabbit IgG AA 1-656 Polyclonal 0
1 ABIN6056275 ELISA FITC Rabbit IgG AA 1-656 Polyclonal 0
1 ABIN6056273 ELISA HRP Rabbit IgG AA 1-656 Polyclonal 0
1 ABIN6116486 ELISA WB Rabbit IgG AA 328-458 Polyclonal 0
1 ABIN6056279 ELISA WB Rabbit IgG AA 1-656 Polyclonal 0
1 ABIN2924279 ELISA WB Rabbit IgG Polyclonal 0
1 ABIN1091400 ELISA WB Rabbit IgG Polyclonal 0
1 ABIN1887911 IHC ELISA WB Rabbit N-Term Polyclonal 0
1 ABIN2959904 IF IHC ELISA WB Rabbit N-Term Polyclonal 0
1 ABIN5704277 ELISA IF IHC IP WB Rabbit IgG Polyclonal 0
1 ABIN5931382 ELISA IF/ICC IHC IP WB Rabbit IgG Polyclonal 0

General

Antigène Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) Anticorps
Épitope pSer161
(18), (13), (8), (8), (7), (7), (7), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivité Humain, Souris
(165), (57), (47), (8), (4), (3), (3), (1), (1)
Hôte Lapin
(137), (31), (3)
Clonalité
Polyclonal
Conjugué Cet anticorp RIPK1 est non-conjugé
(10), (6), (6), (6), (5), (5), (5), (5), (5), (3), (2), (2), (2), (1), (1), (1), (1)
Application ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
(113), (55), (54), (27), (24), (16), (5), (4), (4), (2), (2), (2), (1)
Fournisseur

Détail du produit anti-RIPK1 anticorps

Détail du antigène RIPK1 Information d'application Stockage Images
Specificité Phospho-RIP (Ser361) Antibody detects endogenous levels of RIP only when phosphorylated at Ser361
 Réactivité croisée Humain, Souris
Purification The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Immunogène A synthesized peptide derived from human RIP around the phosphorylation site of Ser361
Isotype IgG
Plasmids, Primers & others

Détail du antigène RIPK1

Détail du produit anti-RIPK1 anticorps Information d'application Stockage Images Haut de la page
Antigène
Autre désignation RIP (RIPK1 Antibody Extrait)
Sujet

Description: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.

Gene: RIPK1

Poids moléculaire 76kDa
ID gène 8737
UniProt Q13546
Pathways Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling

Information d'application

Détail du produit anti-RIPK1 anticorps Détail du antigène RIPK1 Stockage Images Haut de la page
Indications d'application WB 1:500-1:2000, IHC 1:50-1:200
Restrictions For Research Use only

Stockage

Détail du produit anti-RIPK1 anticorps Détail du antigène RIPK1 Information d'application Images Haut de la page
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20 °C.Stable for 12 months from date of receipt
Date de péremption 12 months

Images

Détail du produit anti-RIPK1 anticorps Détail du antigène RIPK1 Information d'application Stockage Haut de la page
Images (Fournisseur)
Immunohistochemistry (IHC) image for anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (pSer161) antibody (ABIN6270166) ABIN6270167 at 1/100 staining mouse kidney tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (pSer161) antibody (ABIN6270166) ABIN6270167 at 1/100 staining human spleen tissue sections by IHC-P. The tissue was f...
Western Blotting (WB) image for anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (pSer161) antibody (ABIN6270166) Western blot analysis of Phospho-RIP (Ser361) in lysates of L-929?, using Phospho-RIP...