anti-Boeuf (Vache) Tumor Necrosis Factor anticorps pour Functional Studies

Recommended Tumor Necrosis Factor Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Tumor Necrosis Factor (TNF) Anticorps
  • DIF
  • TNF-alpha
  • TNFA
  • TNFSF2
  • RATTNF
  • Tnfa
  • tnf
  • TNF-a
  • TNFalpha
  • Tnfsf1a
  • TNFa
  • cTNF
  • Tnf-alpha
  • tnfa-like
  • TNF-ALPHA
  • dif
  • tnfa
  • xtnf
  • tnfsf2
  • tnf-alpha
  • Cachectin
  • tumor necrosis factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • tumor necrosis factor alpha
  • lipopolysaccharide induced TNF factor
  • tumor necrosis factor a (TNF superfamily, member 2)
  • TNF
  • Tnf
  • tnf
  • tnfb
  • tnf-alpha
  • LITAF
  • LOC103694380
  • tnfa
Reactivité
Boeuf (Vache), Chien, Humain, Singe
1380
529
458
228
223
203
202
59
55
43
32
18
15
9
7
6
6
5
4
4
4
4
3
2
2
1
1
1
1
Hôte
Souris
1070
544
138
50
11
10
8
7
5
2
1
Clonalité
Monoclonal
Conjugué
Cet anticorp Tumor Necrosis Factor est non-conjugé
185
95
71
55
49
26
23
22
21
20
19
19
19
19
19
19
18
17
11
11
11
11
11
11
11
11
11
11
11
11
11
11
11
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Functional Studies (Func), Enzyme Immunoassay (EIA)
829
805
756
467
404
269
206
170
134
120
99
66
48
42
26
26
25
17
15
13
9
9
9
7
6
6
6
5
5
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
Fournisseur
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N° du produit ABIN1109393
$ 467.50
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General

Antigène Tumor Necrosis Factor (TNF) Anticorps
Reactivité Boeuf (Vache), Chien, Humain, Singe
(1380), (529), (458), (228), (223), (203), (202), (59), (55), (43), (32), (18), (15), (9), (7), (6), (6), (5), (4), (4), (4), (4), (3), (2), (2), (1), (1), (1), (1)
Hôte Souris
(1070), (544), (138), (50), (11), (10), (8), (7), (5), (2), (1)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp Tumor Necrosis Factor est non-conjugé
(185), (95), (71), (55), (49), (26), (23), (22), (21), (20), (19), (19), (19), (19), (19), (19), (18), (17), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Functional Studies (Func), Enzyme Immunoassay (EIA)
(829), (805), (756), (467), (404), (269), (206), (170), (134), (120), (99), (66), (48), (42), (26), (26), (25), (17), (15), (13), (9), (9), (9), (7), (6), (6), (6), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 2 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-Tumor Necrosis Factor anticorps

Détail du antigène Tumor Necrosis Factor Information d'application Stockage References for anti-Tumor Necrosis Factor antibody (ABIN1109393) Images
Réactivité croisée (Details) Species reactivity (tested):Human, Bovine, Canine, Monkey
Purification Protein G
Clone 5N
Isotype IgG2a
Plasmids, Primers & others

Détail du antigène Tumor Necrosis Factor

Détail du produit anti-Tumor Necrosis Factor anticorps Information d'application Stockage References for anti-Tumor Necrosis Factor antibody (ABIN1109393) Images Haut de la page
Antigène
Autre désignation Tumor Necrosis Factor (TNF-Alpha) (TNF Antibody Extrait)
Sujet Tumor necrosis factor-alpha (TNF-alpha), a homotrimeric 17 KD protein, is a potent mediator of inflammatory and metabolic functions. TNF-alpha was originally detected as a highly cytotoxic cytokine for tumor cells, it causes tumor necrosis in vivo and shows cytolytic activity against tumor cells in vitro. Further TNF-alpha has been implied as central mediator in shock induced by gram negative micro-organisms. The cytokine TNF-alpha is found to be a central mediator in many inflammatory and immunological processes: it can be induced by various products of micro-organisms and by various cytokines but it also induces on its turn the production of many cytokines. Signal transduction occurs via two types of TNF-receptors, the TNF-receptors I and II. The receptors differ strongly in their intra-cellular signaling pathways. The TNF-alpha trimer interacts with either of the two types of TNF-R leading to receptor cross-linking.Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
ID gène 9606
UniProt P01375
Pathways Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus

Information d'application

Détail du produit anti-Tumor Necrosis Factor anticorps Détail du antigène Tumor Necrosis Factor Stockage References for anti-Tumor Necrosis Factor antibody (ABIN1109393) Images Haut de la page
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Stockage

Détail du produit anti-Tumor Necrosis Factor anticorps Détail du antigène Tumor Necrosis Factor Information d'application References for anti-Tumor Necrosis Factor antibody (ABIN1109393) Images Haut de la page
Buffer PBS, 0.1 % bovine serum albumin
Stock 4 °C
Stockage commentaire Store at 2 - 8 °C.

References for anti-Tumor Necrosis Factor antibody (ABIN1109393)

Détail du produit anti-Tumor Necrosis Factor anticorps Détail du antigène Tumor Necrosis Factor Information d'application Stockage Images Haut de la page
Background publications

Song, Fox, Gallo, Rosenberg, Jordan, Shealy, Wagner: "Effects of 2 different anti-tumor necrosis factor-alpha agents in a primate model of subcutaneous abscess formation." dans: The Journal of infectious diseases, Vol. 185, Issue 2, pp. 204-13, 2002

Petyovka, Lyach, Voitenok: "Homologous ELISA for detection of oligomeric human TNF: properties of the assay." dans: Journal of immunological methods, Vol. 186, Issue 2, pp. 161-70, 1995