anti-Souris ADAM17 anticorps pour Enzyme Immunoassay

Recommended ADAM17 Antibody

Antigène
ADAM Metallopeptidase Domain 17 (ADAM17) Anticorps
  • ADAM18
  • CD156B
  • CSVP
  • NISBD
  • TACE
  • CD156b
  • Tace
  • adam17
  • si:dkey-81b15.2
  • adam18
  • cd156b
  • csvp
  • tace
  • fc20b01
  • wu:fc20b01
  • zgc:63886
  • ADAM metallopeptidase domain 17
  • a disintegrin and metallopeptidase domain 17
  • ADAM metallopeptidase domain 17b
  • ADAM metallopeptidase domain 17 L homeolog
  • ADAM metallopeptidase domain 17a
  • ADAM17
  • Adam17
  • adam17b
  • adam17.L
  • adam17a
Épitope
C-Term
62
19
16
11
10
9
8
8
7
6
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
243
95
86
2
2
1
1
1
1
1
Hôte
Lapin
207
22
21
2
1
Clonalité
Polyclonal
Conjugué
Cet anticorp ADAM17 est non-conjugé
14
10
7
6
6
5
4
4
4
4
4
4
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
195
121
45
39
25
14
11
10
10
7
4
3
2
1
1
1
Options
N° du produit ABIN5555290
$ 522.50
Plus shipping costs $45.00

General

Antigène ADAM Metallopeptidase Domain 17 (ADAM17) Anticorps
Épitope C-Term
(62), (19), (16), (11), (10), (9), (8), (8), (7), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(243), (95), (86), (2), (2), (1), (1), (1), (1), (1)
Hôte Lapin
(207), (22), (21), (2), (1)
Clonalité
Polyclonal
Conjugué Cet anticorp ADAM17 est non-conjugé
(14), (10), (7), (6), (6), (5), (4), (4), (4), (4), (4), (4), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(195), (121), (45), (39), (25), (14), (11), (10), (10), (7), (4), (3), (2), (1), (1), (1)
Pubmed 1 référence disponible
Fournisseur

Détail du produit anti-ADAM17 anticorps

Détail du antigène ADAM17 Information d'application Stockage References for anti-ADAM17 antibody (ABIN5555290) Images
Specificité This antibody detects CD156b / ADAM17 at C-term. 80 to 130 kDa bands can be detected, which may represent mature protein, precursor, and glycosylated CD156b.
Réactivité croisée (Details) Species reactivity (tested):Human, Mouse, Rat.
Purification Immunoaffinity Chromatography
Immunogène A peptide corresponding to amino acids near the carboxy terminus of Human CD156b / ADAM17
Isotype IgG
Plasmids, Primers & others

Détail du antigène ADAM17

Détail du produit anti-ADAM17 anticorps Information d'application Stockage References for anti-ADAM17 antibody (ABIN5555290) Images Haut de la page
Antigène
Autre désignation CD156b / ADAM17 (ADAM17 Antibody Extrait)
Sujet Tumor-necrosis factor-a is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-alpha is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-alpha. TNF-alpha converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. TACE is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease). TACE also processes other cell surface proteins, including TNF receptor, TGFa, the L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP) (4,5). TACE mRNA is expressed in a variety of human and murine tissues. TACE was selected as one of the few targets in cytokine activation by the Eighth International Conference of the Inflammation Research Association.Synonyms: CSVP, Disintegrin and metalloproteinase domain-containing protein 17, Snake venom-like protease, TACE, TNF-alpha convertase, TNF-alpha-converting enzyme
ID gène 6868
NCBI Accession NP_003174
Pathways Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus

Information d'application

Détail du produit anti-ADAM17 anticorps Détail du antigène ADAM17 Stockage References for anti-ADAM17 antibody (ABIN5555290) Images Haut de la page
Indications d'application ELISA. Western blot: 1: 500 to 1: 2000. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-ADAM17 anticorps Détail du antigène ADAM17 Information d'application References for anti-ADAM17 antibody (ABIN5555290) Images Haut de la page
Buffer PBS containing 0.02 % Sodium Azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-ADAM17 antibody (ABIN5555290)

Détail du produit anti-ADAM17 anticorps Détail du antigène ADAM17 Information d'application Stockage Images Haut de la page
Produit citée dans:

Wang, Wang, Yin, Zhang, Yu, Kong, Yuan, Fang, Liu, Liu, Shi: "Reduced neurotrophic factor level is the early event before the functional neuronal deficiency in high-fat diet induced obese mice." dans: Metabolic brain disease, Vol. 32, Issue 1, pp. 247-257, 2018